Maternal embryonic leucine zipper kinase: A novel biomarker and a potential therapeutic target of cervical cancer (Q58593899)

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29 April 2020

title

Maternal embryonic leucine zipper kinase: A novel biomarker and a potential therapeutic target of cervical cancer (English)

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cervix uterine cancer

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1

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Jinhua Zhou

7

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29 April 2020

Youguo Chen

8

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author name string

Yamei Wang

2

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29 April 2020

Fangrong Shen

3

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29 April 2020

Yanting Xu

4

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Yinghui Zhang

5

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Xinwei Zou

6

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language of work or name

English

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publication date

18 October 2018

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volume

7

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issue

11

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page(s)

5665-5678

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Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion.

29 April 2020

cites work

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12 December 2020

Gene expression in early stage cervical cancer

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12 December 2020

Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: potential role in progression.

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12 December 2020

Resistance of colorectal cancer cells to radiation and 5-FU is associated with MELK expression

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12 December 2020

The DNA damage response and cancer therapy

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12 December 2020

Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer

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12 December 2020

MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells

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12 December 2020

Inhibiting the DNA damage response as a therapeutic manoeuvre in cancer

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12 December 2020

Maternal embryonic leucine zipper kinase (MELK): a novel regulator in cell cycle control, embryonic development, and cancer

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12 December 2020

MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.

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12 December 2020

Homologous recombination as a replication fork escort: fork-protection and recovery.

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12 December 2020

Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.

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12 December 2020

The DNA damage response: implications for tumor responses to radiation and chemotherapy

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12 December 2020

DNA double-strand break repair inhibitors as cancer therapeutics

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12 December 2020

Global cancer statistics, 2012

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12 December 2020

MELK-a conserved kinase: functions, signaling, cancer, and controversy

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12 December 2020

Treatment Advances in Locoregionally Advanced and Stage IVB/Recurrent Cervical Cancer: Can We Agree That More Is Not Always Better?

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12 December 2020

MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells

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12 December 2020

Maternal embryonic leucine zipper kinase serves as a poor prognosis marker and therapeutic target in gastric cancer

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12 December 2020

Chemotherapy and molecular targeting therapy for recurrent cervical cancer

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12 December 2020

Maternal Embryonic Leucine Zipper Kinase (MELK) as a Novel Mediator and Biomarker of Radioresistance in Human Breast Cancer.

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12 December 2020

Exploiting DNA repair defects for novel cancer therapies

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12 December 2020

MELK expression in ovarian cancer correlates with poor outcome and its inhibition by OTSSP167 abrogates proliferation and viability of ovarian cancer cells

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12 December 2020

Investigational drugs for the treatment of cervical cancer.

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12 December 2020

Antiangiogenics and immunotherapies in cervical cancer: an update and future's view

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12 December 2020

MELK and EZH2 Cooperate to Regulate Medulloblastoma Cancer Stem-like Cell Proliferation and Differentiation

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12 December 2020

MELK: a potential novel therapeutic target for TNBC and other aggressive malignancies.

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12 December 2020

Immunotherapy in ovarian, endometrial and cervical cancer: State of the art and future perspectives

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12 December 2020

p53-independent p21 induction by MELK inhibition

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12 December 2020

Maternal embryonic leucine zipper kinase is a novel target for proliferation-associated high-risk myeloma

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12 December 2020

MicroRNA-214-3p inhibits proliferation and cell cycle progression by targeting MELK in hepatocellular carcinoma and correlates cancer prognosis

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12 December 2020

Up-Regulated Maternal Embryonic Leucine Zipper Kinase Predicts Poor Prognosis of Hepatocellular Carcinoma Patients in a Chinese Han Population.

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12 December 2020

MELK Promotes Melanoma Growth by Stimulating the NF-κB Pathway

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12 December 2020

Comparison of survival outcomes between radical hysterectomy and definitive radiochemotherapy in stage IB1 and IIA1 cervical cancer

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12 December 2020

MELK is a novel therapeutic target in high-risk neuroblastoma

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12 December 2020

MELK expression correlates with tumor mitotic activity but is not required for cancer growth.

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12 December 2020

Chemotherapy and targeted therapy in the management of cervical cancer.

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12 December 2020

Identifiers

DOI

10.1002/CAM4.1816

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PubMed publication ID

30334367

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