Charybdotoxin Binding in the IKs Pore Demonstrates Two MinK Subunits in Each Channel Complex (Q58482877)

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19 December 2019

title

Charybdotoxin binding in the I(Ks) pore demonstrates two MinK subunits in each channel complex (English)

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19 December 2019

2

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19 December 2019

Steve Goldstein

5

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19 December 2019

author name string

Haijun Chen

1

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19 December 2019

Sindhu Rajan

3

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19 December 2019

Shuhua Xu

4

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19 December 2019

language of work or name

English

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publication date

1 September 2003

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19 December 2019

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19 December 2019

volume

40

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19 December 2019

issue

1

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19 December 2019

page(s)

15-23

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A superfamily of small potassium channel subunits: form and function of the MinK-related peptides (MiRPs).

19 December 2019

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Disease-associated mutations in KCNE potassium channel subunits (MiRPs) reveal promiscuous disruption of multiple currents and conservation of mechanism

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Contribution of the S4 segment to gating charge in the Shaker K channel.

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RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K channel function in oocyte expression studies

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K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

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A potassium channel-MiRP complex controls neurosensory function in Caenorhabditis elegans

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Pore- and state-dependent cadmium block of I(Ks) channels formed with MinK-55C and wild-type KCNQ1 subunits

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Electrophysiological consequences of human IKs channel expression in adult murine heart

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Association and stoichiometry of K(ATP) channel subunits

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The Structure of the Potassium Channel: Molecular Basis of K Conduction and Selectivity

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Site-specific mutations in a minimal voltage-dependent K channel alter ion selectivity and open-channel block

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A point mutation in a Shaker K channel changes its charybdotoxin binding site from low to high affinity.

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7 January 2021

Mechanism of charybdotoxin block of a voltage-gated K channel.

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The charybdotoxin receptor of a Shaker K channel: peptide and channel residues mediating molecular recognition

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Transfer of the scorpion toxin receptor to an insensitive potassium channel

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Multiple subunits of a voltage-dependent potassium channel contribute to the binding site for tetraethylammonium

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TEA( )-sensitive KCNQ1 constructs reveal pore-independent access to KCNE1 in assembled I(Ks) channels

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7 January 2021

Subunit stoichiometry of a mammalian K channel determined by construction of multimeric cDNAs.

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Determination of the subunit stoichiometry of a voltage-activated potassium channel

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7 January 2021

Mechanism of charybdotoxin block of the high-conductance, Ca2 -activated K channel

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7 January 2021

Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide inhibitor

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Charybdotoxin, a protein inhibitor of single Ca2 -activated K channels from mammalian skeletal muscle

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Forward transport. 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals

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Spatial localization of the K channel selectivity filter by mutant cycle-based structure analysis.

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7 January 2021

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

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7 January 2021

KCNE1 mutations cause Jervell and Lange-Nielsen syndrome

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7 January 2021

Identification of specific pore residues mediating KCNQ1 inactivation. A novel mechanism for long QT syndrome

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7 January 2021

Single-channel characteristics of wild-type IKs channels and channels formed with two minK mutants that cause long QT syndrome

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7 January 2021

MinK endows the I(Ks) potassium channel pore with sensitivity to internal tetraethylammonium

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7 January 2021

Hyperpolarization moves S4 sensors inward to open MVP, a methanococcal voltage-gated potassium channel

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7 January 2021

Mutations in the hminK gene cause long QT syndrome and suppress lKs function

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7 January 2021

The conduction pore of a cardiac potassium channel

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7 January 2021

Regulation of ion channel expression by cytoplasmic subunits

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7 January 2021

Evidence for dimerization of dimers in K channel assembly

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7 January 2021

min K channels form by assembly of at least 14 subunits

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7 January 2021

Subunit composition of minK potassium channels.

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7 January 2021

MinK residues line a potassium channel pore

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7 January 2021

MinK-KvLQT1 fusion proteins, evidence for multiple stoichiometries of the assembled IsK channel

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7 January 2021

How Does the W434F Mutation Block Current in Shaker Potassium Channels?

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A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels

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Identifiers

DOI

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19 December 2019

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