Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling (Q58450931)

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8 January 2020

title

Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling (English)

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8 January 2020

5

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8 January 2020

author name string

Kavita V Bhatt

1

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8 January 2020

Laurie S Spofford

2

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8 January 2020

Gazelle Aram

3

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8 January 2020

Meghan McMullen

4

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8 January 2020

Andrew E Aplin

6

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8 January 2020

language of work or name

English

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publication date

1 May 2005

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8 January 2020

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8 January 2020

volume

24

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issue

21

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8 January 2020

page(s)

3459-3471

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Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

8 January 2020

cites work

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Regulation of p21(cip1) expression by growth factors and the extracellular matrix reveals a role for transient ERK activity in G1 phase

21 January 2018

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Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity

21 January 2018

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Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression

21 January 2018

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Inhibition of the Phosphoinositide 3-Kinase Pathway Induces a Senescence-like Arrest Mediated by p27Kip1

21 January 2018

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Adhesion-dependent activation of the ERK1/2 cascade is by-passed in melanoma cells

21 January 2018

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The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.

21 January 2018

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Dual stimulation of Ras/mitogen-activated protein kinase and RhoA by cell adhesion to fibronectin supports growth factor-stimulated cell cycle progression

21 January 2018

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MAP kinase-dependent degradation of p27Kip1 by calpains in choroidal melanoma cells. Requirement of p27Kip1 nuclear export

21 January 2018

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Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

21 January 2018

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Multiple ras effector pathways contribute to G(1) cell cycle progression

21 January 2018

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Malignant transformation of melanocytes to melanoma by constitutive activation of mitogen-activated protein kinase kinase (MAPKK) signaling

21 January 2018

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An analysis of Mek1 signaling in cell proliferation and transformation

21 January 2018

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Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

21 January 2018

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Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

21 January 2018

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Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway

21 January 2018

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Activated Raf-1 causes growth arrest in human small cell lung cancer cells

21 January 2018

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Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein

21 January 2018

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Linking cyclins to transcriptional control.

21 January 2018

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7 January 2021

Mutations of the BRAF gene in human cancer

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7 January 2021

Dependence of cyclin E-CDK2 kinase activity on cell anchorage.

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7 January 2021

Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium.

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7 January 2021

Integrins: bidirectional, allosteric signaling machines

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7 January 2021

B-RAF is a therapeutic target in melanoma

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7 January 2021

Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway

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7 January 2021

An anchorage-dependent signal distinct from p42/44 MAP kinase activation is required for cell cycle progression

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7 January 2021

Steroid receptor fusion proteins for conditional activation of Raf-MEK-ERK signaling pathway

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7 January 2021

Vascular endothelial growth factor-mediated activation of p38 is dependent upon Src and RAFTK/Pyk2.

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7 January 2021

Cyclin A is required at two points in the human cell cycle

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7 January 2021

Ras and Rho regulation of the cell cycle and oncogenesis

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7 January 2021

Molecular biology of human melanoma development and progression

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7 January 2021

Molecular mechanisms of human melanocyte attachment to fibronectin

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7 January 2021

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7 January 2021

Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference.

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7 January 2021

Understanding p27(kip1) deregulation in cancer: down-regulation or mislocalization

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208544

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15735667 AND SRC:MED&resulttype=core&format=json

8 January 2020

1 reference