A phase I, open-label, multicenter study to evaluate the pharmacokinetics and safety of oral panobinostat in patients with advanced solid tumors and varying degrees of renal function (Q57696000)

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scientific article published on 07 November 2014

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English	A phase I, open-label, multicenter study to evaluate the pharmacokinetics and safety of oral panobinostat in patients with advanced solid tumors and varying degrees of renal function	scientific article published on 07 November 2014

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25377157 AND SRC:MED&resulttype=core&format=json

22 February 2020

A phase I, open-label, multicenter study to evaluate the pharmacokinetics and safety of oral panobinostat in patients with advanced solid tumors and varying degrees of renal function (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25377157 AND SRC:MED&resulttype=core&format=json

22 February 2020

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ChEBI release 2020-05-28

pharmacokinetics

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based on heuristic

inferred from title

Syed A. Hussain

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25377157 AND SRC:MED&resulttype=core&format=json

22 February 2020

Hans J. Gelderblom

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Hans Gelderblom

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Europe PubMed Central

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22 February 2020

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Sunil Sharma

1

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22 February 2020

Dagmar Hess

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25377157 AND SRC:MED&resulttype=core&format=json

22 February 2020

Edward Waldron

8

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22 February 2020

Song Mu

10

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22 February 2020

Petronella O Witteveen

2

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22 February 2020

Martijn P Lolkema

3

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22 February 2020

Maria G Porro

7

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22 February 2020

Sue-Zette Valera

9

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22 February 2020

publication date

7 November 2014

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22 February 2020

Cancer Chemotherapy and Pharmacology

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25377157 AND SRC:MED&resulttype=core&format=json

22 February 2020

75

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22 February 2020

1

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22 February 2020

87-95

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22 February 2020

Development of the pan-DAC inhibitor panobinostat (LBH589): successes and challenges

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

Histone deacetylase inhibitors in cancer therapy

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

Phase Ia/II, two-arm, open-label, dose-escalation study of oral panobinostat administered via two dosing schedules in patients with advanced hematologic malignancies.

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T-cell lymphoma

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

Panobinostat in patients with relapsed/refractory Hodgkin's lymphoma after autologous stem-cell transplantation: results of a phase II study

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

Phase Ib study of panobinostat and bortezomib in relapsed or relapsed and refractory multiple myeloma.

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

Biocatalytic synthesis and structure elucidation of cyclized metabolites of the deacetylase inhibitor panobinostat (LBH589).

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

Histone deacetylase inhibitors: an overview of the clinical studies in solid tumors

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

Profile of panobinostat and its potential for treatment in solid tumors: an update

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

Panobinostat in lymphoid and myeloid malignancies

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

New generation small-molecule inhibitors in myeloproliferative neoplasms.

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

Panobinostat (LBH589): a potent pan-deacetylase inhibitor with promising activity against hematologic and solid tumors

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

A phase I, open-label, multicenter study to evaluate the pharmacokinetics and safety of oral panobinostat in patients with advanced solid tumors and various degrees of hepatic function

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

Development and validation of ultra high performance liquid chromatography-mass spectrometry method for LBH589 in mouse plasma and tissues.

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

Phase I study of panobinostat and imatinib in patients with treatment-refractory metastatic gastrointestinal stromal tumors

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

The effect of food on the bioavailability of panobinostat, an orally active pan-histone deacetylase inhibitor, in patients with advanced cancer

1 reference

https://api.crossref.org/works/10.1007/S00280-014-2612-8

21 January 2018

Identifiers

10.1007/S00280-014-2612-8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25377157 AND SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25377157 AND SRC:MED&resulttype=core&format=json

22 February 2020

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