Orchestrated regulation of iron trafficking proteins in the kidney during iron overload facilitates systemic iron retention (Q57465684)

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28 April 2020

title

Orchestrated regulation of iron trafficking proteins in the kidney during iron overload facilitates systemic iron retention (English)

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6

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Marianna Truman-Rosentsvit

28 April 2020

7

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Esther G Meyron-Holtz

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author name string

Avital Weiss

1

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Lior Spektor

2

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Lyora A Cohen

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Lena Lifshitz

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Inbar Magid Gold

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Yael Leichtmann-Bardoogo

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Abraham Nyska

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Sefi Addadi

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Tracey A Rouault

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language of work or name

English

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publication date

15 October 2018

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volume

13

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issue

10

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page(s)

e0204471

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Creative Commons CC0 License

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copyright license

start time

15 October 2018

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April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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cites work

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Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice

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Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

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Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2)

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Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network

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The role of Dcytb in iron metabolism: an update

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Iron transport and the kidney

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12 December 2020

Ferroportin 1 is expressed basolaterally in rat kidney proximal tubule cells and iron excess increases its membrane trafficking

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Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway.

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12 December 2020

Dysfunction of the heme recycling system in heme oxygenase 1–deficient mice: effects on macrophage viability and tissue iron distribution

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Human Heme Oxygenase-1 Deficiency Presenting With Hemolysis, Nephritis, and Asplenia

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12 December 2020

Regulation of iron pathways in response to hypoxia

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12 December 2020

Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia

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12 December 2020

Iron insufficiency compromises motor neurons and their mitochondrial function in Irp2-null mice

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Isolation and Characterization of Renal Erythropoietin-Producing Cells from Genetically Produced Anemia Mice

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Ferroportin-mediated iron transport: expression and regulation

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Compartmentalization and regulation of iron metabolism proteins protect male germ cells from iron overload

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Endocytic receptors in the renal proximal tubule.

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12 December 2020

Ferroportin expression in haem oxygenase 1-deficient mice

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Hepcidin regulates intrarenal iron handling at the distal nephron.

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Renal hemosiderosis and rapidly progressive glomerulonephritis associated with primary hemochromatosis

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NCOA4 Deficiency Impairs Systemic Iron Homeostasis

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12 December 2020

Iron Balance and the Role of Hepcidin in Chronic Kidney Disease

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12 December 2020

Erythroid cell mitochondria receive endosomal iron by a "kiss-and-run" mechanism.

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12 December 2020

Endosome-mitochondria interactions are modulated by iron release from transferrin.

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12 December 2020

Hemolytic anemia repressed hepcidin level without hepatocyte iron overload: lesson from Günther disease model

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Ferritin is secreted via two distinct non-classical vesicular pathways.

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12 December 2020

Structure-function analysis of ferroportin defines the binding site and an alternative mechanism of action of hepcidin

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Erythrocytic ferroportin reduces intracellular iron accumulation, hemolysis, and malaria risk.

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12 December 2020

10.1371/JOURNAL.PONE.0204471

Identifiers

DOI

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28 April 2020

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28 April 2020

PubMed publication ID

30321179

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