Interactions between p-33 and p-55 Domains of theHelicobacter pyloriVacuolating Cytotoxin (VacA) (Q57372198)

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20 December 2019

title

Interactions between p-33 and p-55 domains of the Helicobacter pylori vacuolating cytotoxin (VacA) (English)

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20 December 2019

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1

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20 December 2019

Mark S. McClain

2

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20 December 2019

Timothy L. Cover

3

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20 December 2019

author name string

Victor J. Torres

1

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Mark S. McClain

2

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Timothy L. Cover

3

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language of work or name

English

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publication date

30 October 2003

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Journal of Biological Chemistry

20 December 2019

published in

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20 December 2019

volume

279

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20 December 2019

issue

3

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20 December 2019

page(s)

2324-2331

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Unidentified curved bacilli on gastric epithelium in active chronic gastritis

20 December 2019

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Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinoma

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Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration

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Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease

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Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori

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Cytotoxic activity in broth-culture filtrates of Campylobacter pylori

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Vacuoles induced by Helicobacter pylori toxin contain both late endosomal and lysosomal markers

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The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH.

21 January 2018

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Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity.

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Association of Helicobacter pylori vacuolating toxin (VacA) with lipid rafts

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Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin

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The N-terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome c release

21 January 2018

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Vacuolating cytotoxin of Helicobacter pylori induces apoptosis in the human gastric epithelial cell line AGS.

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Selective inhibition of Ii-dependent antigen presentation by Helicobacter pylori toxin VacA.

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Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation

21 January 2018

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Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: structural similarities with the IgA protease type of exported protein

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Carboxy-terminal proteolytic processing of Helicobacter pylori vacuolating toxin.

21 January 2018

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Acid-induced Dissociation of VacA, the Helicobacter pylori Vacuolating Cytotoxin, Reveals Its Pattern of Assembly

21 January 2018

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Oligomeric and subunit structure of the Helicobacter pylori vacuolating cytotoxin

21 January 2018

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3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin

21 January 2018

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Mutational analysis of the Helicobacter pylori vacuolating toxin amino terminus: identification of amino acids essential for cellular vacuolation

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Fluorescence resonance energy transfer microscopy of the Helicobacter pylori vacuolating cytotoxin within mammalian cells

21 January 2018

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Characterization of the C-terminal domain of Helicobacter pylori vacuolating toxin and its relationship with extracellular toxin production

21 January 2018

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Expression and binding analysis of GST-VacA fusions reveals that the C-terminal approximately 100-residue segment of exotoxin is crucial for binding in HeLa cells

21 January 2018

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Essential role of a GXXXG motif for membrane channel formation by Helicobacter pylori vacuolating toxin

21 January 2018

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Multiple oligomeric states of the Helicobacter pylori vacuolating toxin demonstrated by cryo-electron microscopy

21 January 2018

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VacA from Helicobacter pylori: a hexameric chloride channel

21 January 2018

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A 12-amino-acid segment, present in type s2 but not type s1 Helicobacter pylori VacA proteins, abolishes cytotoxin activity and alters membrane channel formation

21 January 2018

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A novel genetic system to detect protein-protein interactions

21 January 2018

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Deletion analysis of GAL4 defines two transcriptional activating segments

21 January 2018

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21 January 2018

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Activation of Helicobacter pylori VacA toxin by alkaline or acid conditions increases its binding to a 250-kDa receptor protein-tyrosine phosphatase beta.

21 January 2018

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Amino-terminal hydrophobic region of Helicobacter pylori vacuolating cytotoxin (VacA) mediates transmembrane protein dimerization.

21 January 2018

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Diversity of protein-protein interactions

21 January 2018

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Channel-forming toxins: tales of transformation

21 January 2018

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Staphylococcal alpha-toxin, streptolysin-O, and Escherichia coli hemolysin: prototypes of pore-forming bacterial cytolysins

21 January 2018

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Structure of the Aeromonas toxin proaerolysin in its water-soluble and membrane-channel states

21 January 2018

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The Vibrio cholerae haemolysin anion channel is required for cell vacuolation and death

21 January 2018

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Oligomerization of the channel-forming toxin aerolysin precedes insertion into lipid bilayers

21 January 2018

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Not as simple as just punching a hole

21 January 2018

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Helicobacter pyloritoxin VacA induces vacuole formation by acting in the cell cytosol

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Amino terminus and the first four membrane-spanning segments of the Arabidopsis K channel KAT1 confer inward-rectification property of plant-animal chimeric channels

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21 January 2018

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Functional complementation reveals the importance of intermolecular monomer interactions for Helicobacter pylori VacA vacuolating activity

21 January 2018

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A dominant negative mutant of Helicobacter pylori vacuolating toxin (VacA) inhibits VacA-induced cell vacuolation

21 January 2018

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Low pH activates the vacuolating toxin of Helicobacter pylori, which becomes acid and pepsin resistant

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M310159200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14593124 AND SRC:MED&resulttype=core&format=json

20 December 2019

1 reference