CD4 Th2 cells are directly regulated by IL-10 during allergic airway inflammation (Q57339873)

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4 April 2020

title

CD4 Th2 cells are directly regulated by IL-10 during allergic airway inflammation (English)

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4

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Riccardo Guidi

5

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4 April 2020

Jimena Perez-Lloret

6

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Werner Müller

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author name string

S M Coomes

1

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Y Kannan

2

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V S Pelly

3

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N Nikolov

7

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M S Wilson

9

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publication date

11 May 2016

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volume

10

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issue

1

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page(s)

150-161

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Creative Commons Attribution 4.0 International

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copyright license

start time

11 May 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Regulatory T cells and IL-10 in allergic inflammation

1 reference

Haplotype associated with low interleukin-10 production in patients with severe asthma

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IL-13Ralpha2 and IL-10 coordinately suppress airway inflammation, airway-hyperreactivity, and fibrosis in mice

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Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosis

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Endogenous interleukin-10 suppresses allergen-induced airway inflammation and nonspecific airway responsiveness

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Eotaxin-2 regulates newly produced and CD34 airway eosinophils after allergen exposure

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Role of interleukin 10 in specific immunotherapy

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IL‐10 and TGF‐β cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy

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Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression

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Memory/effector (CD45RB(lo)) CD4 T cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology

21 January 2018

1 reference

Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3 regulatory CD4 T cells in an interleukin-10-dependent manner

21 January 2018

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Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation

21 January 2018

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In vitro generation of interleukin 10-producing regulatory CD4( ) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

21 January 2018

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Monocytes/macrophages and/or neutrophils are the target of IL-10 in the LPS endotoxemia model

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Exogenous interleukin-10 alleviates allergic inflammation but inhibits local interleukin-10 expression in a mouse allergic rhinitis model

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Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter

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Autoregulation of the Stat3 Gene through Cooperation with a cAMP-responsive Element-binding Protein

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The transcription factor STAT3 is required for T helper 2 cell development

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Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.

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GATA-3 directly remodels the IL-10 locus independently of IL-4 in CD4 T cells.

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Expression of IL-10 in Th memory lymphocytes is conditional on IL-12 or IL-4, unless the IL-10 gene is imprinted by GATA-3.

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Innate immunological function of TH2 cells in vivo.

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IL-10 and regulatory T cells cooperate in allergen-specific immunotherapy to ameliorate allergic asthma

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IL-10 elicits IFNγ-dependent tumor immune surveillance.

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Cytotoxic human CD4( ) T cells

21 January 2018

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CD4( )CD25( ) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

21 January 2018

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Treatment of murine colitis by Lactococcus lactis secreting interleukin-10.

21 January 2018

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A two-step process for cytokine production revealed by IL-4 dual-reporter mice

21 January 2018

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Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter

21 January 2018

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Trimmomatic: a flexible trimmer for Illumina sequence data

21 January 2018

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TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

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HTSeq--a Python framework to work with high-throughput sequencing data

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edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

21 January 2018

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IL-10 CTLA-4 Th2 inhibitory cells form in a Foxp3-independent, IL-2-dependent manner from Th2 effectors during chronic inflammation

21 January 2018

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Activation-induced T helper cell death contributes to Th1/Th2 polarization following murine Schistosoma japonicum infection

21 January 2018

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12 December 2020

Granzyme B is critical for T cell receptor-induced cell death of type 2 helper T cells

1 reference

12 December 2020

IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes

1 reference

12 December 2020

IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells

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12 December 2020

IL-10-overexpressing B cells regulate innate and adaptive immune responses

1 reference

12 December 2020

Regulatory T cells expressing interleukin 10 develop from Foxp3 and Foxp3- precursor cells in the absence of interleukin 10

1 reference

12 December 2020

B7/CD28-dependent IL-5 production by human resting T cells is inhibited by IL-10.

1 reference

12 December 2020

Inhaled corticosteroids increase interleukin-10 but reduce macrophage inflammatory protein-1alpha, granulocyte-macrophage colony-stimulating factor, and interferon-gamma release from alveolar macrophages in asthma

1 reference

12 December 2020

1 reference

12 December 2020

Interleukin-10 regulation in normal subjects and patients with asthma

1 reference

12 December 2020

Identifiers

DOI

10.1038/MI.2016.47

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27166557 AND SRC:MED&resulttype=core&format=json

4 April 2020

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