Simulation and Stability Assessment of Anti-EpCAM Immunotoxin for Cancer Therapy (Q57136183)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30276141 AND SRC:MED&resulttype=core&format=json

25 April 2020

title

Simulation and Stability Assessment of Anti-EpCAM Immunotoxin for Cancer Therapy (English)

1 reference

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25 April 2020

1

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25 April 2020

author name string

Aliakbar Haddad-Mashadrizeh

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30276141 AND SRC:MED&resulttype=core&format=json

25 April 2020

Samaneh Dolatabadi

series ordinal

3

1 reference

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25 April 2020

language of work or name

English

0 references

publication date

29 August 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30276141 AND SRC:MED&resulttype=core&format=json

Advanced Pharmaceutical Bulletin

25 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30276141 AND SRC:MED&resulttype=core&format=json

25 April 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30276141 AND SRC:MED&resulttype=core&format=json

25 April 2020

issue

3

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25 April 2020

page(s)

447-455

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30276141 AND SRC:MED&resulttype=core&format=json

Epithelial cell adhesion molecule-targeted drug delivery for cancer therapy.

25 April 2020

cites work

1 reference

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Epithelial cell adhesion molecule expression (CD326) in cancer: A short review

2 November 2018

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Nuclear signalling by tumour-associated antigen EpCAM

2 November 2018

1 reference

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Modeling recombinant immunotoxin efficacies in solid tumors

2 November 2018

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Epithelial cell adhesion molecule: more than a carcinoma marker and adhesion molecule

2 November 2018

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HA22 (R490A) is a recombinant immunotoxin with increased antitumor activity without an increase in animal toxicity.

2 November 2018

1 reference

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EpCAM is overexpressed in breast cancer and is a potential target for breast cancer gene therapy

2 November 2018

1 reference

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Modeller: generation and refinement of homology-based protein structure models

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6156485

The epithelial cell adhesion molecule (Ep-CAM) as a morphoregulatory molecule is a tool in surgical pathology

2 November 2018

1 reference

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Structure validation by Calpha geometry: phi,psi and Cbeta deviation

2 November 2018

1 reference

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Designing immunotoxins for cancer therapy.

2 November 2018

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Clinical experience with edrecolomab: a monoclonal antibody therapy for colorectal carcinoma

2 November 2018

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Lowering the isoelectric point of the Fv portion of recombinant immunotoxins leads to decreased nonspecific animal toxicity without affecting antitumor activity

2 November 2018

1 reference

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Update of clinical trials with edrecolomab: a monoclonal antibody therapy for colorectal cancer

2 November 2018

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Site-specific chemical modification with polyethylene glycol of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) improves antitumor activity and reduces animal toxicity and immunogenicity

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6156485

The penultimate rotamer library

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6156485

The biology of the 17-1A antigen (Ep-CAM)

2 November 2018

1 reference

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High thermal stability is essential for tumor targeting of antibody fragments: engineering of a humanized anti-epithelial glycoprotein-2 (epithelial cell adhesion molecule) single-chain Fv fragment

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6156485

Prolonged urticaria with 17-1A antibody

2 November 2018

1 reference

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A bivalent disulfide-stabilized Fv with improved antigen binding to erbB2.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6156485

Evaluation of comparative protein structure modeling by MODELLER‐3

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6156485

An Early Step in Pseudomonas Exotoxin Action Is Removal of the Terminal Lysine Residue, Which Allows Binding to the KDEL Receptor

2 November 2018

1 reference

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Sterically stabilized anti-HER2 immunoliposomes: design and targeting to human breast cancer cells in vitro.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6156485

Expression of Ep-CAM in cervical squamous epithelia correlates with an increased proliferation and the disappearance of markers for terminal differentiation

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6156485

Errors in protein structures

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6156485

Identification of residues that stabilize the single-chain Fv of monoclonal antibodies B3.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6156485

A possible three-dimensional structure of bovine α-lactalbumin based on that of hen's egg-white lysozyme

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6156485

Structure determination of turkey egg-white lysozyme using Laue diffraction data

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6156485

Dynamics of folded proteins

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6156485

Colorectal carcinoma-specific antigen: detection by means of monoclonal antibodies

2 November 2018

1 reference

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Edrecolomab (monoclonal antibody 17-1A)

2 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30276141

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reduction of the nonspecific animal toxicity of anti-Tac(Fv)-PE38 by mutations in the framework regions of the Fv which lower the isoelectric point

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30276141

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

In vitro and in vivo activity of MT201, a fully human monoclonal antibody for pancarcinoma treatment

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30276141

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.15171/APB.2018.052

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30276141 AND SRC:MED&resulttype=core&format=json

25 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30276141 AND SRC:MED&resulttype=core&format=json

25 April 2020

PubMed publication ID

30276141

1 reference