Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance (Q57135992)

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scientific article published on 02 August 2018

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English	Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance	scientific article published on 02 August 2018

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25 April 2020

Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance (English)

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25 April 2020

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prostate cancer

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25 April 2020

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Shanique Alabi

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Ryan R Willard

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Nick J Vitale

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Jing Wang

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Hanqing Dong

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Meizhong Jin

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Donald P McDonnell

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Andrew P Crew

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Taavi K Neklesa

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2 August 2018

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Communications Biology

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100

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Neoadjuvant Enzalutamide Prior to Prostatectomy

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Small-Molecule PROTACS: New Approaches to Protein Degradation

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Interaction mechanism exploration of R-bicalutamide/S-1 with WT/W741L AR using molecular dynamics simulations

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Discovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms to androgen signaling-directed prostate cancer therapies

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Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging

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Androgen Receptor Gene Aberrations in Circulating Cell-Free DNA: Biomarkers of Therapeutic Resistance in Castration-Resistant Prostate Cancer

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Androgen receptor as a driver of therapeutic resistance in advanced prostate cancer

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Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer

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Enzalutamide: a review of its use in metastatic, castration-resistant prostate cancer

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An F876L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (enzalutamide).

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Targeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α Interaction

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7 January 2021

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Bafilomycin A1, a specific inhibitor of vacuolar-type H( )-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells

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https://pubmed.ncbi.nlm.nih.gov/30271980

12 December 2020

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