ABCB1 Single-Nucleotide Polymorphisms Determine Tacrolimus Response in Patients With Ulcerative Colitis (Q57072058)

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23 November 2024

author name string

K. R. Herrlinger

1

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23 November 2024

H. Koc

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S. Winter

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A. Teml

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23 November 2024

E. F. Stange

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K. Fellermann

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P. Fritz

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E. Schaeffeler

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Clinical Pharmacology & Therapeutics

23 November 2024

language of work or name

English

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publication date

2 February 2011

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published in

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volume

89

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issue

3

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page(s)

422-428

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cites work

Review article: saving the colon in severe colitis - the case for medical therapy

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A randomised dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis

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Response of refractory colitis to intravenous or oral tacrolimus (FK506).

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Effect of oral tacrolimus (FK 506) on steroid-refractory moderate/severe ulcerative colitis

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Tacrolimus is safe and effective in patients with severe steroid-refractory or steroid-dependent inflammatory bowel disease--a long-term follow-up

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Long-term effect of tacrolimus therapy in patients with refractory ulcerative colitis.

21 January 2018

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Genetic polymorphisms of the human MDR1 drug transporter

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Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

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Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part II.

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Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part I.

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Frequency of C3435T polymorphism of MDR1 gene in African people

21 January 2018

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Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis.

21 January 2018

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Decreased sigmoidal ABCB1 (P-glycoprotein) expression in ulcerative colitis is associated with disease activity.

21 January 2018

1 reference

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A "silent" polymorphism in the MDR1 gene changes substrate specificity

21 January 2018

1 reference

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Alterations of CYP3A4 and P-glycoprotein activity in vivo with time in renal graft recipients

21 January 2018

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Tacrolimus. A review of its pharmacology, and therapeutic potential in hepatic and renal transplantation

21 January 2018

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Tacrolimus is a class II low-solubility high-permeability drug: the effect of P-glycoprotein efflux on regional permeability of tacrolimus in rats

21 January 2018

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Local application of tacrolimus in distal colitis: feasible and safe

21 January 2018

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Rectal tacrolimus in the treatment of resistant ulcerative proctitis

21 January 2018

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Differential effect of diarrhea on FK506 versus cyclosporine A trough levels and resultant prevention of allograft rejection in renal transplant recipients.

21 January 2018

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Local immune regulation of mucosal inflammation by tacrolimus

21 January 2018

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Clinical and genetic risk factors for posttransplant diabetes mellitus in adult renal transplant recipients treated with tacrolimus

21 January 2018

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Opportunities to optimize tacrolimus therapy in solid organ transplantation: report of the European consensus conference

21 January 2018

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CYP2C19 and nongenetic factors predict poor responsiveness to clopidogrel loading dose after coronary stent implantation

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Haploview: analysis and visualization of LD and haplotype maps

21 January 2018

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The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study

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7 January 2021

Oral tacrolimus treatment of severe colitis in children

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7 January 2021

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

1 reference

https://api.crossref.org/works/10.1038/CLPT.2010.348

7 January 2021

Preliminary report: cyclosporin in treatment of severe active ulcerative colitis

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7 January 2021

Association of the P-glycoprotein transporter MDR1(C3435T) polymorphism with the susceptibility to renal epithelial tumors

1 reference

https://api.crossref.org/works/10.1038/CLPT.2010.348

7 January 2021

Infliximab as rescue medication for patients with severe ulcerative/indeterminate colitis refractory to tacrolimus

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1 reference

DOI

10.1038/CLPT.2010.348

https://api.crossref.org/works/10.1038/CLPT.2010.348

23 November 2024

Identifiers

DOI

10.1038/CLPT.2010.348

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