Genetic Influences on the Pharmacokinetics of Orally and Intravenously Administered Digoxin as Exhibited by Monozygotic Twins (Q56981756)

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Friedrich Luft

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object named as

F C Luft

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author name string

A L Birkenfeld

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J Jordan

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G Franke

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N Krüger

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S Igel

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T Mürdter

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S Drescher

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S Shi

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S Engeli

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M Schwab

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M Eichelbaum

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M F Fromm

Clinical Pharmacology & Therapeutics

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language of work or name

English

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publication date

23 September 2009

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published in

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volume

86

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issue

6

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page(s)

605-608

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cites work

Predicting drug disposition, absorption/elimination/transporter interplay and the role of food on drug absorption

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Drug-drug interactions mediated through P-glycoprotein: clinical relevance and in vitro-in vivo correlation using digoxin as a probe drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Importance of P-glycoprotein at blood-tissue barriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Transporters and drug therapy: implications for drug disposition and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Gene and protein expression of P-glycoprotein, MRP1, MRP2, and CYP3A4 in the small and large human intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Cytochrome P450 3A4 and P-glycoprotein expression in human small intestinal enterocytes and hepatocytes: a comparative analysis in paired tissue specimens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Effects of a chargrilled meat diet on expression of CYP3A, CYP1A, and P-glycoprotein levels in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Carbamazepine regulates intestinal P-glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Identification of functionally variant MDR1 alleles among European Americans and African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Impact of genetic polymorphisms of transporters on the pharmacokinetic, pharmacodynamic and toxicological properties of anionic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Genetic polymorphisms of the human MDR1 drug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4-dependent pharmacokinetics in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Effects of pregnancy on CYP3A and P-glycoprotein activities as measured by disposition of midazolam and digoxin: a University of Washington specialized center of research study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Heritability of free and receptor-bound leptin in normal twins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

The interindividual differences in the 3-demthylation of caffeine alias CYP1A2 is determined by both genetic and environmental factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Bioavailability of imipramine tablets relative to a stable isotope-labeled internal standard: Increasing the power of bioavailability tests

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

A "silent" polymorphism in the MDR1 gene changes substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

C825T polymorphism in the human G protein beta3 subunit gene is associated with long-term clozapine treatment-induced body weight change in the Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

Increased absorption of digoxin from the human jejunum due to inhibition of intestinal transporter-mediated efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

7 January 2021

Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine*

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

7 January 2021

P-glycoprotein increases from proximal to distal regions of human small intestine

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

7 January 2021

Further characterization of a furanocoumarin-free grapefruit juice on drug disposition: studies with cyclosporine

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

7 January 2021

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

7 January 2021

Steady-state plasma levels of nortriptyline in twins: influence of genetic factors and drug therapy

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

7 January 2021

Hypothesis: comparisons of inter- and intra-individual variations can substitute for twin studies in drug research

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

7 January 2021

Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability

1 reference

https://api.crossref.org/works/10.1038/CLPT.2009.170

7 January 2021