Directed evolution of hydrolases for prevention of G-type nerve agent intoxication (Q56896643)

11

0 references

author name string

Rinkoo D Gupta

1

0 references

Moshe Goldsmith

2

0 references

Yacov Ashani

3

0 references

Yair Simo

4

0 references

Gavriel Mullokandov

5

0 references

Hagit Bar

6

0 references

Moshe Ben-David

7

0 references

Haim Leader

8

0 references

Raanan Margalit

9

0 references

Israel Silman

10

0 references

Joel L Sussman

11

0 references

Dan S Tawfik

Bioscavengers for the protection of humans against organophosphate toxicity

12

0 references

language of work or name

English

0 references

publication date

February 2011

0 references

9 January 2011

0 references

published in

Nature Chemical Biology

0 references

volume

7

0 references

issue

2

0 references

page(s)

120-5

0 references

120-125

0 references

cites work

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Stoichiometric and catalytic scavengers as protection against nerve agent toxicity: a mini review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Estimation of the Upper Limit of Human Butyrylcholinesterase Dose Required for Protection against Organophosphates Toxicity: a Mathematically Based Toxicokinetic Model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

In search of a catalytic bioscavenger for the prophylaxis of nerve agent toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Detoxification of organophosphate nerve agents by bacterial phosphotriesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Functional analysis of organophosphorus hydrolase variants with high degradation activity towards organophosphate pesticides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Reversed enantioselectivity of diisopropyl fluorophosphatase against organophosphorus nerve agents by rational design

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Stereoselective hydrolysis of organophosphate nerve agents by the bacterial phosphotriesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Prophylaxis against organophosphate poisoning by an enzyme hydrolysing organophosphorus compounds in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Paraoxonase protects against chlorpyrifos toxicity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of soman poisoning in rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Stereoselective detoxification of chiral sarin and soman analogues by phosphotriesterase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Enhanced stereoselective hydrolysis of toxic organophosphates by directly evolved variants of mammalian serum paraoxonase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

In vivo administration of BL-3050: highly stable engineered PON1-HDL complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Stereo-specific synthesis of analogs of nerve agents and their utilization for selection and characterization of paraoxonase (PON1) catalytic scavengers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Directed enzyme evolution via small and effective neutral drift libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

High-throughput screening of enzyme libraries: thiolactonases evolved by fluorescence-activated sorting of single cells in emulsion compartments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

High-throughput screening of enzyme libraries: in vitro evolution of a beta-galactosidase by fluorescence-activated sorting of double emulsions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Incorporating Synthetic Oligonucleotides via Gene Reassembly (ISOR): a versatile tool for generating targeted libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Mechanism for potent reactivation ability of H oximes analyzed by reactivation kinetic studies with cholinesterases from different species

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Addressing the numbers problem in directed evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Improving catalytic function by ProSAR-driven enzyme evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Directed evolution of a magnetic resonance imaging contrast agent for noninvasive imaging of dopamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NCHEMBIO.510

Asymmetric fluorogenic organophosphates for the development of active organophosphate hydrolases with reversed stereoselectivity

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21217689

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A purified recombinant organophosphorus acid anhydrase protects mice against soman

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21217689