Phase I trial of DNA-hsp65 immunotherapy for advanced squamous cell carcinoma of the head and neck (Q56786021)

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8 January 2020

title

Phase I trial of DNA-hsp65 immunotherapy for advanced squamous cell carcinoma of the head and neck (English)

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8 January 2020

main subject

phase I clinical trial

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immunotherapy

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head and neck squamous cell carcinoma

inferred from title

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5

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8 January 2020

Gabriel Victora

7

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Carlos Rodrigo Zárate-Bladés

8 January 2020

10

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Paulo Andrade Lotufo

18

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8 January 2020

Célio L Silva

21

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8 January 2020

author name string

P Michaluart

1

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8 January 2020

K A Abdallah

2

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8 January 2020

F D Lima

3

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8 January 2020

R Smith

4

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8 January 2020

V Coelho

6

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8 January 2020

A Socorro-Silva

8

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8 January 2020

E C Volsi

9

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8 January 2020

A R Ferraz

11

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8 January 2020

A K Barreto

12

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8 January 2020

M C Chammas

13

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8 January 2020

R Gomes

14

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8 January 2020

E Gebrim

15

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8 January 2020

L Arakawa-Sugueno

16

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K P Fernandes

17

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8 January 2020

M R Cardoso

19

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8 January 2020

J Kalil

20

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publication date

6 June 2008

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8 January 2020

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volume

15

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issue

10

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page(s)

676-684

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Loss of p53 expression correlates with metastatic phenotype and transcriptional profile in a new mouse model of head and neck cancer.

8 January 2020

cites work

1 reference

Evolution of patients with squamous cell carcinoma of upper aerodigestive tract

21 January 2018

1 reference

Postoperative chemoradiotherapy for advanced squamous cell carcinoma of the head and neck: a systematic review with meta-analysis

21 January 2018

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Phase II and biologic study of interferon alfa, retinoic acid, and cisplatin in advanced squamous skin cancer

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21 January 2018

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The Group II Chaperonin TRiC Protects Proteolytic Intermediates from Degradation in the MHC Class I Antigen Processing Pathway

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The Mycobacterium leprae hsp65 displays proteolytic activity. Mutagenesis studies indicate that the M. leprae hsp65 proteolytic activity is catalytically related to the HslVU protease

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Tumor cell membrane-bound heat shock protein 70 elicits antitumor immunity

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A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition

21 January 2018

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21 January 2018

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21 January 2018

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Immunotherapy with plasmid DNA encoding mycobacterial hsp65 in association with chemotherapy is a more rapid and efficient form of treatment for tuberculosis in mice.

21 January 2018

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Tumor cells transfected with a bacterial heat-shock gene lose tumorigenicity and induce protection against tumors

21 January 2018

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Improved efficacy of DNA vaccination against breast cancer by boosting with the repeat beta-hCG C-terminal peptide carried by mycobacterial heat-shock protein HSP65.

21 January 2018

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Rifapentine, moxifloxacin, or DNA vaccine improves treatment of latent tuberculosis in a mouse model

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Validation overview of bio-analytical methods

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New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

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Efficacy of DNA-hsp65 vaccination for tuberculosis varies with method of DNA introduction in vivo

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DNA vaccines for therapy of tuberculosis: where are we now?

21 January 2018

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Enumeration of T cells reactive with Mycobacterium tuberculosis organisms and specific for the recombinant mycobacterial 64-kDa protein

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Adenoviral gene therapy in head and neck cancer

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7 January 2021

Phase I/II trial of erlotinib and cisplatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck: a Princess Margaret Hospital phase II consortium and National Cancer Institute of Canada Clinical Trials Group Study

1 reference

7 January 2021

Phase I study of highly selective supradose cisplatin infusions for advanced head and neck cancer

1 reference

7 January 2021

Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer

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7 January 2021

Chaperones as part of immune networks.

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7 January 2021

Association of peptides with heat shock protein gp96 occurs in vivo and not after cell lysis

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7 January 2021

Immune regulatory effect of pHSP65 DNA therapy in pulmonary tuberculosis: activation of CD8 cells, interferon-gamma recovery and reduction of lung injury

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7 January 2021

Heat shock proteins refine the danger theory

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7 January 2021

Gene therapy for cancer treatment: past, present and future

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7 January 2021

Naked DNA and adenoviral immunizations for immunotherapy of prostate cancer: a phase I/II clinical trial.

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7 January 2021

Identifiers

DOI

10.1038/CGT.2008.35

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18535616 AND SRC:MED&resulttype=core&format=json

8 January 2020

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