FOXO1 regulates the expression of 4E-BP1 and inhibits mTOR signaling in mammalian skeletal muscle (Q56743003)

Dataset for "Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine"

Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

title

FOXO1 regulates the expression of 4E-BP1 and inhibits mTOR signaling in mammalian skeletal muscle (English)

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author name string

Robert J Southgate

1

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Bronwyn Neill

2

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Oja Prelovsek

3

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Assam El-Osta

4

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Yasutomi Kamei

5

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Shinji Miura

6

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Osamu Ezaki

7

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Thomas J McLoughlin

8

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Wenwei Zhang

9

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Terry G Unterman

10

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Mark A Febbraio

Journal of Biological Chemistry

11

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language of work or name

English

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publication date

20 July 2007

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published in

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volume

282

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issue

29

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page(s)

21176-86

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cites work

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Balancing muscle hypertrophy and atrophy

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The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors

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Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

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Degradation of MyoD mediated by the SCF (MAFbx) ubiquitin ligase

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The FOXO3a transcription factor regulates cardiac myocyte size downstream of AKT signaling

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Nutritional and hormonal factors control the gene expression of FoxOs, the mammalian homologues of DAF-16

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Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

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Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

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Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B

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Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

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Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation

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Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation?

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TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function

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Signal transduction pathways that regulate eukaryotic protein synthesis

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Identification of phosphorylation sites in the translational regulator, PHAS-I, that are controlled by insulin and rapamycin in rat adipocytes

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mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

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Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

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The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif

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Upstream and downstream of mTOR

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The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling

21 January 2018

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Drosophila Melted modulates FOXO and TOR activity.

21 January 2018

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The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span

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FoxO1 stimulates fatty acid uptake and oxidation in muscle cells through CD36-dependent and -independent mechanisms.

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Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence

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Polyamines regulate eukaryotic initiation factor 4E-binding protein 1 gene transcription

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A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

21 January 2018

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Regulation of insulin-like growth factor-dependent myoblast differentiation by Foxo forkhead transcription factors

21 January 2018

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FoxO proteins in insulin action and metabolism

21 January 2018

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Regulation of cellular growth by the Drosophila target of rapamycin dTOR

21 January 2018

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Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

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The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila

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Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control.

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Interaction of FoxO1 and TSC2 induces insulin resistance through activation of the mammalian target of rapamycin/p70 S6K pathway

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Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism

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Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells

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Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

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FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression

21 January 2018

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