Tissue-type plasminogen activator as a therapeutic target in stroke (Q56336828)

Expert Opinion on Therapeutic Targets

Europe PubMed Central

title

Tissue-type plasminogen activator as a therapeutic target in stroke (English)

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1 reference

Iordanis Gravanis

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Stella E Tsirka

series ordinal

2

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language of work or name

English

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publication date

February 2008

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published in

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volume

12

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issue

2

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page(s)

159-70

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cites work

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Modulation of zinc toxicity by tissue plasminogen activator

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Neuronal cell death and tPA.

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Recombinant tissue plasminogen activator reduces infarct size after reversible thread occlusion of middle cerebral artery in mice

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Tissue plasminogen activator does not increase neuronal damage in rat models of global and focal ischemia

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Tissue plasminogen activator-induced ischemic injury is reversed by NMDA antagonist MK-801 in vivo

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Neutralizing the neurotoxic effects of exogenous and endogenous tPA.

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LRP and alphavbeta3 mediate tPA activation of smooth muscle cells

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Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein.

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Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration

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Identifiers

DOI

0 references

Fatcat ID

release_dhcp6wugfzfa3djwific4svhne

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/dhcp6wugfzfa3djwific4svhne

24 November 2022