APOE ε4 status in healthy older African Americans is associated with deficits in pattern separation and hippocampal hyperactivation (Q56333867)

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31 March 2020

title

APOE ε4 status in healthy older African Americans is associated with deficits in pattern separation and hippocampal hyperactivation (English)

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31 March 2020

author name string

Neha Sinha

1

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31 March 2020

Chelsie N Berg

2

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31 March 2020

Ashlee Shaw

4

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31 March 2020

Diane Hill

5

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31 March 2020

Mark A Gluck

7

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31 March 2020

language of work or name

English

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publication date

26 May 2018

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31 March 2020

published in

Neurobiology of Aging

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31 March 2020

volume

69

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31 March 2020

page(s)

221-229

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Dyspnoea, disability, and distance walked: comparison of estimates of exercise performance in respiratory disease

31 March 2020

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Hippocampal activation in patients with mild cognitive impairment is necessary for successful memory encoding

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Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults

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Apolipoprotein E4 causes age- and Tau-dependent impairment of GABAergic interneurons, leading to learning and memory deficits in mice

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Multiplexed echo planar imaging for sub-second whole brain FMRI and fast diffusion imaging

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Hippocampal hyperactivation in presymptomatic familial Alzheimer's disease

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Longitudinal modeling of frontal cognition in APOE ε4 homozygotes, heterozygotes, and noncarriers

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A comprehensive genetic association study of Alzheimer disease in African Americans

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Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment

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Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans

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Effect of socioeconomic disparities on incidence of dementia among biracial older adults: prospective study

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Sex modifies the APOE-related risk of developing Alzheimer disease

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Performance on a pattern separation task by Alzheimer's patients shows possible links between disrupted dentate gyrus activity and apolipoprotein E ∈4 status and cerebrospinal fluid amyloid-β42 levels

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Using timed up and go and usual gait speed to predict incident disability in daily activities among community-dwelling adults aged 65 and older.

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APOE ε4: the most prevalent yet understudied risk factor for Alzheimer's disease

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Response of the medial temporal lobe network in amnestic mild cognitive impairment to therapeutic intervention assessed by fMRI and memory task performance

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Spatial pattern separation differences in older adult carriers and non-carriers for the apolipoprotein E epsilon 4 allele

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Increased hippocampal activation in ApoE-4 carriers and non-carriers with amnestic mild cognitive impairment.

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Frequency Specific Effects of ApoE ε4 Allele on Resting-State Networks in Nondemented Elders.

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Differential Aging Trajectories of Modulation of Activation to Cognitive Challenge in APOE ε4 Groups: Reduced Modulation Predicts Poorer Cognitive Performance.

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Integrating new findings and examining clinical applications of pattern separation

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12 December 2020

10.1016/J.NEUROBIOLAGING.2018.05.023

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29909179 AND SRC:MED&resulttype=core&format=json

31 March 2020

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31 March 2020

PubMed publication ID

29909179

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