Diosmetin suppresses human prostate cancer cell proliferation through the induction of apoptosis and cell cycle arrest. (Q55331844)

http://europepmc.org/abstract/PMC/6017185

2 July 2018

title

Diosmetin suppresses human prostate cancer cell proliferation through the induction of apoptosis and cell cycle arrest. (English)

1 reference

http://europepmc.org/abstract/PMC/6017185

2 July 2018

author

Ahmad Khalifa

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29767250 AND SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Christine Oak

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29767250 AND SRC:MED&resulttype=core&format=json

13 June 2020

Ilaha Isali

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29767250 AND SRC:MED&resulttype=core&format=json

13 June 2020

Natarajan Bhaskaran

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29767250 AND SRC:MED&resulttype=core&format=json

13 June 2020

Ethan Walker

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29767250 AND SRC:MED&resulttype=core&format=json

13 June 2020

Sanjeev Shukla

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29767250 AND SRC:MED&resulttype=core&format=json

13 June 2020

publication date

16 May 2018

1 reference

http://europepmc.org/abstract/PMC/6017185

2 July 2018

published in

International Journal of Oncology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29767250 AND SRC:MED&resulttype=core&format=json

13 June 2020

volume

53

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29767250 AND SRC:MED&resulttype=core&format=json

13 June 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29767250 AND SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

835-843

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29767250 AND SRC:MED&resulttype=core&format=json

Radiosensitizing effect of diosmetin on radioresistant lung cancer cells via Akt signaling pathway.

13 June 2020

cites work

1 reference

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Diosmetin induces cell apoptosis by regulating CYP1A1/CYP1A2 due to p53 activation in HepG2 cells

3 July 2018

1 reference

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Diosmetin inhibits cell proliferation and induces apoptosis by regulating autophagy via the mammalian target of rapamycin pathway in hepatocellular carcinoma HepG2 cells

3 July 2018

1 reference

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3 July 2018

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The emerging role of obesity, diet and lipid metabolism in prostate cancer

3 July 2018

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The stress hormone norepinephrine increases migration of prostate cancer cells in vitro and in vivo

3 July 2018

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3 July 2018

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Differential metabolomic analysis of the potential antiproliferative mechanism of olive leaf extract on the JIMT-1 breast cancer cell line.

3 July 2018

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3 July 2018

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Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control

3 July 2018

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Confirmation of diosmetin 3-O-glucuronide as major metabolite of diosmin in humans, using micro-liquid-chromatography-mass spectrometry and ion mobility mass spectrometry

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Antagonism between FOXO and MYC Regulates Cellular Powerhouse

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and P53/P21 up-regulation.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

3 July 2018

1 reference

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The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy

3 July 2018

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Overexpression of C-MYC oncogene in prostate cancer predicts biochemical recurrence

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Anticancer effects of the flavonoid diosmetin on cell cycle progression and proliferation of MDA-MB 468 breast cancer cells due to CYP1 activation.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Bioactivation of the phytoestrogen diosmetin by CYP1 cytochromes P450.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Simultaneous determination of the flavonoid aglycones diosmetin and hesperetin in human plasma and urine by a validated GC/MS method: in vivo metabolic reduction of diosmetin to hesperetin

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

c-Myc represses FOXO3a-mediated transcription of the gene encoding the p27(Kip1) cyclin dependent kinase inhibitor

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

CDK inhibitors: cell cycle regulators and beyond

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Cyclin-dependent kinase pathways as targets for cancer treatment

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Biochemical and cellular mechanisms of mammalian CDK inhibitors: a few unresolved issues

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Clinical anticancer drug development: targeting the cyclin-dependent kinases

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Complexities in the development of cyclin-dependent kinase inhibitor drugs

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Diosmetin Induces Apoptosis of Acute Myeloid Leukemia Cells.

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Development of cell-cycle inhibitors for cancer therapy

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Analysis of cell cycle by flow cytometry

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Resistance of MCF-7 cells to dimethylbenz(a)anthracene-induced apoptosis is due to reduced CYP1A1 expression

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

A transgenic mouse model with cyclin D1 overexpression results in cell cycle, epidermal growth factor receptor, and p53 abnormalities

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Prostate cancer susceptibility and growth linked to Y chromosome genes

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Inhibition of Cytochrome P450 2C8-mediated Drug Metabolism by the Flavonoid Diosmetin

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6017185

Pharmacokinetics and metabolism of oral diosmin in healthy volunteers

30 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29767250

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Molecular aspects of the mammalian cell cycle and cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29767250

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Body mass index was associated with upstaging and upgrading in patients with low-risk prostate cancer who met the inclusion criteria for active surveillance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29767250

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3892/IJO.2018.4407

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29767250 AND SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29767250 AND SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

29767250

1 reference