PDK1: a new therapeutic target for glioblastoma? (Q55072763)

17 June 2018

editorial

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title

PDK1: a new therapeutic target for glioblastoma? (English)

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17 June 2018

author name string

Kiran Kumar Velpula

series ordinal

1

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17 June 2018

Andrew J Tsung

series ordinal

2

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17 June 2018

publication date

1 May 2014

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17 June 2018

published in

CNS oncology

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17 June 2018

volume

3

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17 June 2018

issue

3

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17 June 2018

page(s)

177-179

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17 June 2018

Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma

cites work

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On the Origin of Cancer Cells

21 January 2018

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Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism

21 January 2018

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Combined targeting of PDK1 and EGFR triggers regression of glioblastoma by reversing the Warburg effect

21 January 2018

1 reference

A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence.

21 January 2018

1 reference

Expression parameters of the metabolic pathway genes pyruvate dehydrogenase kinase-1 (PDK-1) and DJ-1/PARK7 in renal cell carcinoma (RCC).

21 January 2018

1 reference

Pyruvate dehydrogenase and pyruvate dehydrogenase kinase expression in non small cell lung cancer and tumor-associated stroma

21 January 2018

1 reference

PDK-1 regulates lactate production in hypoxia and is associated with poor prognosis in head and neck squamous cancer

21 January 2018

1 reference

Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells

21 January 2018

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HIF1α modulates cell fate reprogramming through early glycolytic shift and upregulation of PDK1-3 and PKM2.

21 January 2018

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Metabolic modulation of glioblastoma with dichloroacetate

21 January 2018

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A mitochondria-K channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

21 January 2018

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Phenylbutyrate therapy for pyruvate dehydrogenase complex deficiency and lactic acidosis.

21 January 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6124368

Expression of pyruvate dehydrogenase kinase-1 in gastric cancer as a potential therapeutic target

2 November 2018

1 reference

PubMed Central

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6124368

2 November 2018

Identifiers

DOI

10.2217/CNS.14.13

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17 June 2018

PMC publication ID

6124368

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17 June 2018