Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form. (Q54615293)

1 June 2018

title

Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form. (English)

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1 June 2018

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Scheffzek K

1

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Klebe C

2

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Fritz-Wolf K

3

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Kabsch W

4

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Wittinghofer A

5

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language of work or name

English

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publication date

1 March 1995

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1 June 2018

published in

Nature

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volume

374

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issue

6520

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page(s)

378-381

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The ras protein family: evolutionary tree and role of conserved amino acids

cites work

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7 January 2021

The GTPase superfamily: a conserved switch for diverse cell functions

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7 January 2021

Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide

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7 January 2021

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

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7 January 2021

Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor

1 reference

7 January 2021

Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progression

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7 January 2021

Effects of mutant Ran/TC4 proteins on cell cycle progression.

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7 January 2021

Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

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7 January 2021

The structure of Ras protein: a model for a universal molecular switch

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7 January 2021

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

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7 January 2021

Structure of the GDP domain of EF-Tu and location of the amino acids homologous to ras oncogene proteins

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7 January 2021

Crystal structure of active elongation factor Tu reveals major domain rearrangements

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7 January 2021

The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S

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7 January 2021

Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

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7 January 2021

The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution

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7 January 2021

Functional expression in Escherichia coli of the mitotic regulator proteins p24ran and p45rcc1 and fluorescence measurements of their interaction

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7 January 2021

The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA

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7 January 2021

RanGAP1 induces GTPase activity of nuclear Ras-related Ran

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7 January 2021

Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4

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7 January 2021

Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1

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7 January 2021

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

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7 January 2021

Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP

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7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

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7 January 2021

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

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7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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7 January 2021

Identifiers

DOI

10.1038/374378A0

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1 June 2018

Dimensions Publication ID

1029800227

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1 June 2018