Nonredundant roles of TIRAP and MyD88 in airway response to endotoxin, independent of TRIF, IL-1 and IL-18 pathways. (Q54455445)

30 May 2018

title

Nonredundant roles of TIRAP and MyD88 in airway response to endotoxin, independent of TRIF, IL-1 and IL-18 pathways. (English)

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30 May 2018

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9

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Isabelle Couillin

12

object named as

Isabelle Couillin

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Bernhard Ryffel

11

object named as

Bernhard Ryffel

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10

Bruce Beutler

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1

Dieudonnée Togbe

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30 May 2018

Nicolas Noulin

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object named as

Nicolas Noulin

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30 May 2018

author name string

Gorse Aurore

2

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30 May 2018

Valérie F J Quesniaux

4

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30 May 2018

Silvia Schnyder-Candrian

5

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Bruno Schnyder

6

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Virginie Vasseur

7

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Shizuo Akira

8

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30 May 2018

Isabelle Couillin

12

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30 May 2018

publication date

18 September 2006

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30 May 2018

published in

Laboratory Investigation

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30 May 2018

volume

86

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30 May 2018

issue

11

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30 May 2018

page(s)

1126-1135

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30 May 2018

The role of endotoxin in grain dust-induced lung disease

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The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

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Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

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TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

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Both hemopoietic and resident cells are required for MyD88-dependent pulmonary inflammatory response to inhaled endotoxin

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Toll-IL-1 receptor domain-containing adaptor protein is critical for early lung immune responses against Escherichia coli lipopolysaccharide and viable Escherichia coli

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MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction

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ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance

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Severity of asthma is related to endotoxin in house dust

21 January 2018

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7 January 2021

Variable airway responsiveness to inhaled lipopolysaccharide

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7 January 2021

Lipopolysaccharide-induced leukocyte-endothelial cell interactions: a role for CD14 versus toll-like receptor 4 within microvessels

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7 January 2021

TLR4 gene dosage contributes to endotoxin-induced acute respiratory inflammation

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7 January 2021

Unresponsiveness of MyD88-deficient mice to endotoxin

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7 January 2021

IL-1 can act as number one

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7 January 2021

Chronic pneumonia despite adaptive immune response to Mycobacterium bovis BCG in MyD88-deficient mice

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7 January 2021

Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1038/LABINVEST.3700473

Identifiers

DOI

10.1038/LABINVEST.3700473

1 reference

30 May 2018

1 reference

30 May 2018