Prognostic value of TOP2A gene amplification and chromosome 17 polysomy in early breast cancer. (Q54318735)

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26 January 2020

title

Prognostic value of TOP2A gene amplification and chromosome 17 polysomy in early breast cancer (English)

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Anna Supernat

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Natalia Bednarz-Knoll

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Jaroslaw Skokowski

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Jacek Jassem

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Wojciech Biernat

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Piotr Czapiewski

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26 January 2020

Aleksandra Markiewicz

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Aleksandra Markiewicz

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Barbara Seroczyńska

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Jolanta Szade

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Marzena Wełnicka-Jaśkiewicz

26 January 2020

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object named as

Marzena Wełnicka-Jaśkiewicz

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author name string

Burkhardt Brandt

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26 January 2020

publication date

18 March 2012

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Pathology and Oncology Research

26 January 2020

published in

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volume

18

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issue

4

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26 January 2020

page(s)

885-894

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Detection of gene amplification in archival breast cancer specimens by laser-assisted microdissection and quantitative real-time polymerase chain reaction

26 January 2020

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Breast cancer and aneusomy 17: implications for carcinogenesis and therapeutic response

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Poor prognostic significance of unamplified chromosome 17 polysomy in invasive breast carcinoma.

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Chromosome 17 aneusomy is associated with poor prognostic factors in invasive breast carcinoma

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Amplification and deletion of topoisomerase IIalpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer

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Clinical evaluation of developed PCR-based method with hydrolysis probes for TOP2A copy number evaluation in breast cancer samples.

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Assessment of Topoisomerase II α status in breast cancer by quantitative PCR, gene expression microarrays, immunohistochemistry, and fluorescence in situ hybridization

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Association between HER2, TOP2A, and response to anthracycline-based preoperative chemotherapy in high-risk primary breast cancer

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Alterations in the TOP2A and HER2 genes: association with adjuvant anthracycline sensitivity in human breast cancers

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Clinicopathologic analysis of breast carcinoma with chromosomal aneusomy detected by fluorescence in situ hybridization

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Aneusomy 17 in breast cancer: its role in HER-2/neu protein expression and implication for clinical assessment of HER-2/neu status

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Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray-based CGH analysis

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Chromosome 17 polysomy without human epidermal growth factor receptor 2 amplification does not predict response to lapatinib plus paclitaxel compared with paclitaxel in metastatic breast cancer.

21 January 2018

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BRCA1 loss preexisting in small subpopulations of prostate cancer is associated with advanced disease and metastatic spread to lymph nodes and peripheral blood

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Polysomy of chromosome 17 in breast cancer tumors showing an overexpression of ERBB2: a study of 175 cases using fluorescence in situ hybridization and immunohistochemistry

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Patterns of Aneusomy for Three Chromosomes in Individual Cells from Breast Cancer Tumors

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