TRIM28 prevents autoinflammatory T cell development in vivo. (Q54312343)

27 May 2018

title

TRIM28 prevents autoinflammatory T cell development in vivo. (English)

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27 May 2018

5

Tasuku Honjo

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Il-Mi Okazaki

object named as

Il-Mi Okazaki

3

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author name string

Shunsuke Chikuma

1

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27 May 2018

Naomasa Suita

2

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27 May 2018

Shiro Shibayama

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27 May 2018

language of work or name

English

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publication date

29 April 2012

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27 May 2018

published in

Nature Immunology

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27 May 2018

volume

13

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issue

6

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27 May 2018

page(s)

596-603

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27 May 2018

T cell antigen receptor signal transduction pathways

cites work

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Th17: an effector CD4 T cell lineage with regulatory T cell ties

21 January 2018

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Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation

21 January 2018

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

21 January 2018

1 reference

Transforming growth factor-beta induces development of the T(H)17 lineage

21 January 2018

1 reference

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

21 January 2018

1 reference

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

21 January 2018

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Preferential generation of follicular B helper T cells from Foxp3 T cells in gut Peyer's patches

21 January 2018

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Late developmental plasticity in the T helper 17 lineage

21 January 2018

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The tripartite motif family identifies cell compartments

21 January 2018

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KAP-1, a novel corepressor for the highly conserved KRAB repression domain

21 January 2018

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Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1

21 January 2018

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Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family

21 January 2018

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SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins

21 January 2018

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TRIM28 mediates primer binding site-targeted silencing of murine leukemia virus in embryonic cells

21 January 2018

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KAP1 controls endogenous retroviruses in embryonic stem cells

21 January 2018

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KAP1, a novel substrate for PIKK family members, colocalizes with numerous damage response factors at DNA lesions

21 January 2018

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53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair

21 January 2018

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Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway

21 January 2018

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TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

21 January 2018

1 reference

The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA

21 January 2018

1 reference

Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation

21 January 2018

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Phosphoproteomic analysis reveals an intrinsic pathway for the regulation of histone deacetylase 7 that controls the function of cytotoxic T lymphocytes

21 January 2018

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Phosphorylation at Ser473 regulates heterochromatin protein 1 binding and corepressor function of TIF1beta/KAP1.

21 January 2018

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Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes

21 January 2018

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Functional competence of T cells in the absence of glycosylphosphatidylinositol-anchored proteins caused by T cell-specific disruption of the Pig-a gene

21 January 2018

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From naive to effector ‐ alterations with aging

21 January 2018

1 reference

Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

21 January 2018

1 reference

IL-2, regulatory T cells, and tolerance

21 January 2018

1 reference

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

21 January 2018

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Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity

21 January 2018

1 reference

Human transforming growth factor-beta 3: recombinant expression, purification, and biological activities in comparison with transforming growth factors-beta 1 and -beta 2.

21 January 2018

1 reference

In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

21 January 2018

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Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

21 January 2018

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Spontaneous elaboration of transforming growth factor beta suppresses host defense against bacterial infection in autoimmune MRL/lpr mice

21 January 2018

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The role of IL-23/IL-17 axis in lupus nephritis

21 January 2018

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Intracellular demonstration of active TGFbeta1 in B cells and plasma cells of autoimmune mice. IgG-bound TGFbeta1 suppresses neutrophil function and host defense against Staphylococcus aureus infection

21 January 2018

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The functional class evaluated in rheumatoid arthritis is associated with soluble TGF-β1 serum levels but not with G915C (Arg25Pro) TGF-β1 polymorphism.

21 January 2018

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Autocrine Transforming Growth Factor-β1 Promotes In Vivo Th17 Cell Differentiation

21 January 2018

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Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation

21 January 2018

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Induction and regulation of inflammatory bowel disease in immunodeficient mice by distinct CD4 T-cell subsets.

21 January 2018

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Thymic selection of CD4 CD25 regulatory T cells induced by an agonist self-peptide

21 January 2018

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12 December 2020

Origin of regulatory T cells with known specificity for antigen

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12 December 2020

Mice lacking the transcriptional corepressor TIF1beta are defective in early postimplantation development.

1 reference

12 December 2020

Aberrant wound healing and TGF-beta production in the autoimmune-prone MRL/ mouse

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12 December 2020

A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors

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12 December 2020

Identifiers

DOI

10.1038/NI.2293

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27 May 2018

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27 May 2018