Suppressing the formation of lipid raft-associated Rac1/PI3K/Akt signaling complexes by curcumin inhibits SDF-1α-induced invasion of human esophageal carcinoma cells. (Q54281504)

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English	Suppressing the formation of lipid raft-associated Rac1/PI3K/Akt signaling complexes by curcumin inhibits SDF-1α-induced invasion of human esophageal carcinoma cells.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/23192861

Suppressing the formation of lipid raft-associated Rac1/PI3K/Akt signaling complexes by curcumin inhibits SDF-1α-induced invasion of human esophageal carcinoma cells. (English)

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/23192861

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based on heuristic

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esophageal carcinoma

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based on heuristic

inferred from title

Jing-Gung Chung

5

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Jing-Gung Chung

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Europe PubMed Central

PubMed publication ID

27 May 2018

author name string

Meng-Liang Lin

1

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/23192861

Yao-Cheng Lu

2

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/23192861

Hung-Yi Chen

3

1 reference

Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/23192861

Chuan-Chun Lee

4

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/23192861

Shih-Shun Chen

6

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/23192861

publication date

28 November 2012

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/23192861

Molecular Carcinogenesis

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/23192861

53

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/23192861

5

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Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/23192861

360-379

1 reference

Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/23192861

The role of CXC chemokines and their receptors in cancer.

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Involvement of chemokine receptors in breast cancer metastasis

1 reference

https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Lipid rafts and little caves. Compartmentalized signalling in membrane microdomains

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Growth factor receptors, lipid rafts and caveolae: an evolving story

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

CXCL12/CXCR4 transactivates HER2 in lipid rafts of prostate cancer cells and promotes growth of metastatic deposits in bone

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21 January 2018

Omega-3 polyunsaturated fatty acids down-modulate CXCR4 expression and function in MDA-MB-231 breast cancer cells

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Leukocyte-endothelium interaction promotes SDF-1-dependent polarization of CXCR4.

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21 January 2018

Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient

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21 January 2018

The phosphoinositide 3-kinase pathway

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Advances in protein kinase B signalling: AKTion on multiple fronts

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

PI3K/Akt and apoptosis: size matters

1 reference

https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Akt signaling regulates actin organization via modulation of MMP-2 activity during chondrogenesis of chick wing limb bud mesenchymal cells.

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Overexpression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Matrix metalloproteinase-2: mechanism and regulation of NF-kappaB-mediated activation and its role in cell motility and ECM-invasion.

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21 January 2018

An essential role for Rac in Ras transformation

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Rho Family GTPases Bind to Phosphoinositide Kinases

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Involvement of matrix metalloproteinase-9 in stromal cell-derived factor-1/CXCR4 pathway of lung cancer metastasis

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

TCR signal initiation machinery is pre-assembled and activated in a subset of membrane rafts

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Association of dengue virus NS1 protein with lipid rafts

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Rac GTPase interacts specifically with phosphatidylinositol 3-kinase

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Regulation of CXCR4 conformation by the small GTPase Rac1: implications for HIV infection

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Effects of cholesterol depletion by cyclodextrin on the sphingolipid microdomains of the plasma membrane

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Potential role of NF-kappaB in esophageal adenocarcinoma: as an emerging molecular target.

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Overexpression of phosphorylated nuclear factor-kappa B in tonsillar squamous cell carcinoma and high-grade dysplasia is associated with poor prognosis.

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Crosstalk between BCR/ABL oncoprotein and CXCR4 signaling through a Src family kinase in human leukemia cells

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Integrins regulate Rac targeting by internalization of membrane domains

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

The role of chemokine activation of Rac GTPases in hematopoietic stem cell marrow homing, retention, and peripheral mobilization

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Rac and Rho GTPases in cancer cell motility control

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Inhibitory effect of curcumin on IMP dehydrogenase, the target for anticancer and antiviral chemotherapy agents

1 reference

https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Regulation of Cell–Cell Adhesion by Rac and Rho Small G Proteins in MDCK Cells

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21 January 2018

Novel regulation by Rac1 of glucose- and forskolin-induced insulin secretion in INS-1 beta-cells

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Akt protein kinase inhibits Rac1-GTP binding through phosphorylation at serine 71 of Rac1.

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells

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21 January 2018

Amino acids interfere with the ERK1/2-dependent control of macroautophagy by controlling the activation of Raf-1 in human colon cancer HT-29 cells

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells

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21 January 2018

Curcumin prevents adriamycin nephrotoxicity in rats

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21 January 2018

Curcumin attenuation of acute adriamycin myocardial toxicity in rats

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21 January 2018

Curcumin induces apoptosis-independent death in oesophageal cancer cells.

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21 January 2018

Curcumin induces cell death in esophageal cancer cells through modulating Notch signaling

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Structure and function of phosphoinositide 3-kinases.

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21 January 2018

FGFR2-Cbl interaction in lipid rafts triggers attenuation of PI3K/Akt signaling and osteoblast survival

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Crumbs controls epithelial integrity by inhibiting Rac1 and PI3K

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

RhoA and Rac1 GTPases play major and differential roles in stromal cell-derived factor-1-induced cell adhesion and chemotaxis in multiple myeloma.

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1.

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https://api.crossref.org/works/10.1002/MC.21984

21 January 2018

Down-regulation of MMP-2 through the p38 MAPK-NF-kappaB-dependent pathway by aloe-emodin leads to inhibition of nasopharyngeal carcinoma cell invasion

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23 March 2024

Identifiers

10.1002/MC.21984

1 reference

Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/23192861

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 May 2018

http://europepmc.org/abstract/MED/23192861

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