MAP2K1 and MAP3K1 mutations in Langerhans cell histiocytosis. (Q54276385)

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6 March 2020

title

MAP2K1 and MAP3K1 mutations in Langerhans cell histiocytosis (English)

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Gayane Badalian-Very

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Barrett J Rollins

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author name string

David S Nelson

1

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Astrid van Halteren

2

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Willemijn T Quispel

3

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Cor van den Bos

4

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Bhumi Patel

6

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Paul van Hummelen

8

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Matthew Ducar

9

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Ling Lin

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Laura E MacConaill

11

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R Maarten Egeler

12

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publication date

31 March 2015

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Genes, Chromosomes and Cancer

6 March 2020

published in

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volume

54

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issue

6

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page(s)

361-368

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Cell-specific gene expression in Langerhans cell histiocytosis lesions reveals a distinct profile compared with epidermal Langerhans cells

6 March 2020

cites work

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Recurrent BRAF mutations in Langerhans cell histiocytosis

21 January 2018

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Pathogenesis of Langerhans cell histiocytosis.

21 January 2018

1 reference

Biology of Langerhans cells and Langerhans cell histiocytosis

21 January 2018

1 reference

BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups

21 January 2018

1 reference

High prevalence of somatic MAP2K1 mutations in BRAF V600E-negative Langerhans cell histiocytosis.

21 January 2018

1 reference

Comprehensive molecular portraits of human breast tumours

21 January 2018

1 reference

Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.

21 January 2018

1 reference

Langerhans cell histiocytosis: fascinating dynamics of the dendritic cell-macrophage lineage.

21 January 2018

1 reference

MEK1 mutations confer resistance to MEK and B-RAF inhibition

21 January 2018

1 reference

Combinations of BRAF, MEK, and PI3K/mTOR inhibitors overcome acquired resistance to the BRAF inhibitor GSK2118436 dabrafenib, mediated by NRAS or MEK mutations

21 January 2018

1 reference

Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation

21 January 2018

1 reference

Differential Activation of Two JNK Activators, MKK7 and SEK1, by MKN28-derived Nonreceptor Serine/Threonine Kinase/Mixed Lineage Kinase 2

21 January 2018

1 reference

Identification of the V600D mutation in Exon 15 of the BRAF oncogene in congenital, benign langerhans cell histiocytosis.

21 January 2018

1 reference

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

21 January 2018

1 reference

Somatic activating ARAF mutations in Langerhans cell histiocytosis.

21 January 2018

1 reference

BRAFV600E mutant protein is expressed in cells of variable maturation in Langerhans cell histiocytosis.

21 January 2018

1 reference

B-RAF mutant alleles associated with Langerhans cell histiocytosis, a granulomatous pediatric disease

21 January 2018

1 reference

Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine

21 January 2018

1 reference

Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling

21 January 2018

1 reference

High prevalence of MAP2K1 mutations in variant and IGHV4-34-expressing hairy-cell leukemias

21 January 2018

1 reference

MEK Kinase 1, a Substrate for DEVD-Directed Caspases, Is Involved in Genotoxin-Induced Apoptosis

21 January 2018

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Langerhans'-cell histiocytosis (histiocytosis X)--a clonal proliferative disease.

21 January 2018

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Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

21 January 2018

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Whole-genome analysis informs breast cancer response to aromatase inhibition

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identification of two essential phosphorylated threonine residues in the catalytic domain of Mekk1. Indirect activation by Pak3 and protein kinase C

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Clonal proliferation of Langerhans cells in Langerhans cell histiocytosis

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/GCC.22247

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6 March 2020

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