Endostatin gene therapy delivered by attenuated Salmonella typhimurium in murine tumor models. (Q54213329)

26 May 2018

title

Endostatin gene therapy delivered by attenuated Salmonella typhimurium in murine tumor models. (English)

1 reference

26 May 2018

main subject

gene therapy

0 references

Salmonella Typhimurium

1 reference

Kang Liang

1

1 reference

26 May 2018

Qing Liu

2

1 reference

26 May 2018

Pei Li

3

1 reference

26 May 2018

Yue Han

4

1 reference

26 May 2018

Xiaoping Bian

5

1 reference

26 May 2018

Yibo Tang

6

1 reference

26 May 2018

Qingke Kong

7

1 reference

26 May 2018

publication date

14 May 2018

1 reference

26 May 2018

published in

Cancer Gene Therapy

1 reference

26 May 2018

Salmonella as an innovative therapeutic antitumor agent.

cites work

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Tumor-specific colonization, tissue distribution, and gene induction by probiotic Escherichia coli Nissle 1917 in live mice

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Lipid A mutant Salmonella with suppressed virulence and TNFalpha induction retain tumor-targeting in vivo

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

In tumors Salmonella migrate away from vasculature toward the transition zone and induce apoptosis

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Trg-deficient Salmonella colonize quiescent tumor regions by exclusively penetrating or proliferating

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Engineering the perfect (bacterial) cancer therapy

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Cancer immunotherapy based on killing of Salmonella-infected tumor cells

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Salmonella-mediated tumor regression involves targeting of tumor myeloid suppressor cells causing a shift to M1-like phenotype and reduction in suppressive capacity

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Enhanced therapeutic effect by combination of tumor-targeting Salmonella and endostatin in murine melanoma model

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Enhanced therapeutic effect of cisplatin on the prostate cancer in tumor-bearing mice by transfecting the attenuated Salmonella carrying a plasmid co-expressing p53 gene and mdm2 siRNA.

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

A phase I clinical study to evaluate safety of orally administered, genetically engineered Salmonella enterica serovar Typhimurium for canine osteosarcoma.

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Pilot trial of genetically modified, attenuated Salmonella expressing the E. coli cytosine deaminase gene in refractory cancer patients

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Cancer metastasis directly eradicated by targeted therapy with a modified Salmonella typhimurium

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Tumor-seeking Salmonella amino acid auxotrophs

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Intraperitoneal administration of tumor-targeting Salmonella typhimurium A1-R inhibits disseminated human ovarian cancer and extends survival in nude mice

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Targeted therapy with a Salmonella typhimurium leucine-arginine auxotroph cures orthotopic human breast tumors in nude mice

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Innate recognition of lipopolysaccharide by Toll-like receptor 4-MD-2.

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Lipopolysaccharide endotoxins

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Noncanonical inflammasome activation by intracellular LPS independent of TLR4.

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Host response: new LPS receptors discovered

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Molecular basis of reduced potency of underacylated endotoxins

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Endostatin's emerging roles in angiogenesis, lymphangiogenesis, disease, and clinical applications.

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Antiangiogenesis signals by endostatin.

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1.

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1.

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Nucleolin is a receptor that mediates antiangiogenic and antitumor activity of endostatin

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Phase II study of recombinant human endostatin in patients with advanced neuroendocrine tumors

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Antitumor effects of Stat3-siRNA and endostatin combined therapies, delivered by attenuated Salmonella, on orthotopically implanted hepatocarcinoma

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Delivery of the co-expression plasmid pEndo-Si-Stat3 by attenuated Salmonella serovar typhimurium for prostate cancer treatment

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Selenium-Bifidobacterium longum as a delivery system of endostatin for inhibition of pathogenic bacteria and selective regression of solid tumor

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

New technologies in developing recombinant attenuated Salmonella vaccine vectors

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Effect of deletion of genes involved in lipopolysaccharide core and O-antigen synthesis on virulence and immunogenicity of Salmonella enterica serovar typhimurium

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

RGD Peptide Cell-Surface Display Enhances the Targeting and Therapeutic Efficacy of Attenuated Salmonella-mediated Cancer Therapy

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Emerging roles of caspase-3 in apoptosis

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Purification and characterization of the L-Ara4N transferase protein ArnT from Salmonella typhimurium.

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Activation of PmrA inhibits LpxT-dependent phosphorylation of lipid A promoting resistance to antimicrobial peptides

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Lipid A modification systems in gram-negative bacteria

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Motility is critical for effective distribution and accumulation of bacteria in tumor tissue

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Salmonella typhimurium lacking ribose chemoreceptors localize in tumor quiescence and induce apoptosis

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Influence of infection route and virulence factors on colonization of solid tumors bySalmonella entericaserovar Typhimurium

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Tumor invasion of Salmonella enterica serovar Typhimurium is accompanied by strong hemorrhage promoted by TNF-alpha

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Enterobacterial tumor colonization in mice depends on bacterial metabolism and macrophages but is independent of chemotaxis and motility

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimurium

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Two-step enhanced cancer immunotherapy with engineered Salmonella typhimurium secreting heterologous flagellin

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

The Boosting Potential of Bacteria in Cancer Immunotherapy

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Salmonella synthesizing 1-dephosphorylated [corrected] lipopolysaccharide exhibits low endotoxic activity while retaining its immunogenicity.

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Growth-phase regulation of lipopolysaccharide O-antigen chain length influences serum resistance in serovars of Salmonella.

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

The Salmonella PmrAB regulon: lipopolysaccharide modifications, antimicrobial peptide resistance and more

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Efficiency of conditionally attenuated Salmonella enterica serovar Typhimurium in bacterium-mediated tumor therapy.

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Toxicology and efficacy of tumor-targeting Salmonella typhimurium A1-R compared to VNP 20009 in a syngeneic mouse tumor model in immunocompetent mice.

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

High-throughput screening for salmonella avirulent mutants that retain targeting of solid tumors

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Explicit hypoxia targeting with tumor suppression by creating an "obligate" anaerobic Salmonella Typhimurium strain

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Local application of bacteria improves safety of Salmonella -mediated tumor therapy and retains advantages of systemic infection.

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Intratumoral injection of attenuated Salmonella vaccine can induce tumor microenvironmental shift from immune suppressive to immunogenic

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Targeted Cancer Therapy Using Engineered Salmonella typhimurium

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Salmonella-Mediated Cancer Therapy: Roles and Potential

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Engineering of bacteria for the visualization of targeted delivery of a cytolytic anticancer agent

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Salmonella typhimurium Suppresses Tumor Growth via the Pro-Inflammatory Cytokine Interleukin-1β.

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Activation of inflammasome by attenuated Salmonella typhimurium in bacteria-mediated cancer therapy

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Lipid A controls the robustness of intratumoral accumulation of attenuated Salmonella in mice

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Biodistribution and genetic stability of the novel antitumor agent VNP20009, a genetically modified strain of Salmonella typhimurium

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Palmitoylation state impacts induction of innate and acquired immunity by the Salmonella enterica serovar typhimurium msbB mutant

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Phosphate groups of lipid A are essential for Salmonella enterica serovar Typhimurium virulence and affect innate and adaptive immunity

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

New horizons in adjuvants for vaccine development

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Potent and tumor specific: arming bacteria with therapeutic proteins

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Vessel destruction by tumor-targetingSalmonella typhimuriumA1-R is enhanced by high tumor vascularity

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Control of colonization by virulent Salmonella typhimurium by oral immunization of chickens with avirulent delta cya delta crp S. typhimurium

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

Immune responses to recombinant pneumococcal PspA antigen delivered by live attenuated Salmonella enterica serovar typhimurium vaccine

1 reference

https://api.crossref.org/works/10.1038/S41417-018-0021-6

7 January 2021

10.1038/S41417-018-0021-6

Identifiers

DOI

1 reference

26 May 2018

1 reference

26 May 2018