Domains of human topoisomerase I and associated functions. (Q54137858)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9863573 AND SRC:MED&resulttype=core&format=json

11 November 2019

review article

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title

Domains of human topoisomerase I and associated functions (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9863573 AND SRC:MED&resulttype=core&format=json

11 November 2019

author name string

J J Champoux

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9863573 AND SRC:MED&resulttype=core&format=json

11 November 2019

publication date

1 January 1998

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9863573 AND SRC:MED&resulttype=core&format=json

Progress in Molecular Biology and Translational Science

11 November 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9863573 AND SRC:MED&resulttype=core&format=json

11 November 2019

volume

60

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9863573 AND SRC:MED&resulttype=core&format=json

11 November 2019

page(s)

111-132

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11 November 2019

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Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I

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A 26 kDa yeast DNA topoisomerase I fragment: crystallographic structure and mechanistic implications

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Crystal structure of an N-terminal fragment of the DNA gyrase B protein.

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Structure and mechanism of DNA topoisomerase II

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The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I.

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7 January 2021

Sequence-dependent effect of camptothecin on human topoisomerase I DNA cleavage

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7 January 2021

New technique for uncoupling the cleavage and religation reactions of eukaryotic topoisomerase I. The mode of action of camptothecin at a specific recognition site

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7 January 2021

Patterns of strongly protein-associated simian virus 40 DNA replication intermediates resulting from exposures to specific topoisomerase poisons

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7 January 2021

DNA topoisomerase-targeting antitumor drugs can be studied in yeast

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7 January 2021

The creation of a camptothecin-sensitive Escherichia coli based on the expression of the human topoisomerase I

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7 January 2021

SCT1 mutants suppress the camptothecin sensitivity of yeast cells expressing wild-type DNA topoisomerase I

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7 January 2021

Eukaryotic DNA topoisomerases I.

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cDNA cloning of human DNA topoisomerase I: catalytic activity of a 67.7-kDa carboxyl-terminal fragment

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Cloning and characterization of the gene for the somatic form of DNA topoisomerase I from Xenopus laevis

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Isolation and characterization of a gene encoding DNA topoisomerase I in Drosophila melanogaster

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cDNA cloning, expression, and chromosomal localization of Caenorhabditis elegans DNA topoisomerase I.

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7 January 2021

Cloning, characterization, and sequence of the yeast DNA topoisomerase I gene

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Cloning and sequencing of Schizosaccharomyces pombe DNA topoisomerase I gene, and effect of gene disruption.

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The gene encoding topoisomerase I from the human malaria parasite Plasmodium falciparum

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The topoisomerase I gene from Ustilago maydis: sequence, disruption and mutant phenotype

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Characterization of purified DNA-relaxing enzyme from human tissue culture cells

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Purification and characterization of the DNA untwisting enzyme from rat liver

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Biochemical and biophysical analyses of recombinant forms of human topoisomerase I

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Eukaryotic DNA topoisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei

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Expression of yeast DNA topoisomerase I can complement a conditional-lethal DNA topoisomerase I mutation in Escherichia coli

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Nuclear targeting sequences--a consensus?

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Cloning of yeast TOP1, the gene encoding DNA topoisomerase I, and construction of mutants defective in both DNA topoisomerase I and DNA topoisomerase II.

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Need for DNA topoisomerase activity as a swivel for DNA replication for transcription of ribosomal RNA

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Mitotic chromosome condensation in the rDNA requires TRF4 and DNA topoisomerase I in Saccharomyces cerevisiae.

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Identification of a nucleolin binding site in human topoisomerase I

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Supercoiling of the DNA template during transcription

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Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes.

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Discrete localization of different DNA topoisomerases in HeLa and K562 cell nuclei and subnuclear fractions

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Nuclear export of proteins: the role of nuclear retention.

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Nuclear shuttling: the default pathway for nuclear proteins?

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Drosophila DNA topoisomerase I is associated with transcriptionally active regions of the genome

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Topoisomerase I interacts with transcribed regions in Drosophila cells.

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Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene

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Rapid induction of c-fos transcription reveals quantitative linkage of RNA polymerase II and DNA topoisomerase I enzyme activities

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DNA topoisomerase I is involved in both repression and activation of transcription

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Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II.

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Topoisomerase I enhances TFIID-TFIIA complex assembly during activation of transcription

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7 January 2021

Simian virus 40 large T antigen binds to topoisomerase I.

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7 January 2021

Quantitation of eukaryotic topoisomerase I reactivity with DNA. Preferential cleavage of supercoiled DNA

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Eukaryotic DNA topoisomerase I reaction is topology dependent

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Regulation of the function of eukaryotic DNA topoisomerase I: topological conditions for inactivity

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Regulation of the function of eukaryotic DNA topoisomerase I: analysis of the binding step and of the catalytic constants of topoisomerization as a function of DNA topology

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Reconstitution of human topoisomerase I by fragment complementation

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Peptide sequencing and site-directed mutagenesis identify tyrosine-727 as the active site tyrosine of Saccharomyces cerevisiae DNA topoisomerase I.

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Purification and characterization of human topoisomerase I mutants

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Phenotypic selection and characterization of mutant alleles of a eukaryotic DNA topoisomerase I.

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Mutations within a conserved region of vaccinia topoisomerase affect the DNA cleavage-religation equilibrium

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Histidine 265 is important for covalent catalysis by vaccinia topoisomerase and is conserved in all eukaryotic type I enzymes

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Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA

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A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in Tetrahymena R-chromatin.

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Mapping in vivo topoisomerase I sites on simian virus 40 DNA: asymmetric distribution of sites on replicating molecules

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Analysis of the biased distribution of topoisomerase I break sites on replicating simian virus 40 DNA.

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Induction of cleavage in topoisomerase I c-DNA by topoisomerase I enzymes from calf thymus and wheat germ in the presence and absence of camptothecin

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On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex

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Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites

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Detection of topoisomerase I gene point mutation in CPT-11 resistant lung cancer cell line

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A camptothecin-resistant DNA topoisomerase I mutant exhibits altered sensitivities to other DNA topoisomerase poisons

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Structure of eukaryotic type I DNA topoisomerase.

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9863573 AND SRC:MED&resulttype=core&format=json

11 November 2019

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