Stereoselective Inhibition of Methotrexate Excretion by Glucuronides of Nonsteroidal Anti-inflammatory Drugs via Multidrug Resistance Proteins 2 and 4. (Q53805550)

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scientific article published on 9 December 2015

Language	Label	Description	Also known as
English	Stereoselective Inhibition of Methotrexate Excretion by Glucuronides of Nonsteroidal Anti-inflammatory Drugs via Multidrug Resistance Proteins 2 and 4.	scientific article published on 9 December 2015

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 May 2018

http://europepmc.org/abstract/MED/26659924

Stereoselective Inhibition of Methotrexate Excretion by Glucuronides of Nonsteroidal Anti-inflammatory Drugs via Multidrug Resistance Proteins 2 and 4. (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 May 2018

http://europepmc.org/abstract/MED/26659924

multiple drug resistance

1 reference

based on heuristic

inferred from title

stereoselectivity

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Atsushi Kawase

1

1 reference

Europe PubMed Central

PubMed publication ID

19 May 2018

http://europepmc.org/abstract/MED/26659924

Taiki Yamamoto

2

1 reference

Europe PubMed Central

PubMed publication ID

19 May 2018

http://europepmc.org/abstract/MED/26659924

Sachiko Egashira

3

1 reference

Europe PubMed Central

PubMed publication ID

19 May 2018

http://europepmc.org/abstract/MED/26659924

Masahiro Iwaki

4

1 reference

Europe PubMed Central

PubMed publication ID

19 May 2018

http://europepmc.org/abstract/MED/26659924

language of work or name

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publication date

9 December 2015

1 reference

Europe PubMed Central

PubMed publication ID

19 May 2018

http://europepmc.org/abstract/MED/26659924

Journal of Pharmacology and Experimental Therapeutics

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Europe PubMed Central

PubMed publication ID

19 May 2018

http://europepmc.org/abstract/MED/26659924

356

1 reference

Europe PubMed Central

PubMed publication ID

19 May 2018

http://europepmc.org/abstract/MED/26659924

2

1 reference

Europe PubMed Central

PubMed publication ID

19 May 2018

http://europepmc.org/abstract/MED/26659924

366-374

1 reference

Europe PubMed Central

PubMed publication ID

19 May 2018

http://europepmc.org/abstract/MED/26659924

Prolongation and enhancement of serum methotrexate concentrations by probenecid

1 reference

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Acyl glucuronide reactivity in perspective: biological consequences

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Predictability of the covalent binding of acidic drugs in man.

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Pharmacokinetic and pharmacodynamic differences between two low dosages of aspirin may affect therapeutic outcomes

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Interaction between methotrexate and ciprofloxacin

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Clinical pharmacokinetics of diclofenac. Therapeutic insights and pitfalls

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Clinical pharmacokinetics of naproxen

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Interaction of nonsteroidal anti-inflammatory drugs with multidrug resistance protein (MRP) 2/ABCC2- and MRP4/ABCC4-mediated methotrexate transport

1 reference

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Methotrexate and nonsteroidal antiinflammatory drug interactions

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Stereoselective disposition of flurbiprofen in healthy subjects following administration of the single enantiomers

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Variability in the stereoselective disposition of ibuprofen in patients with rheumatoid arthritis

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Stereoselective inhibition by the diastereomers quinidine and quinine of uptake of cardiac glycosides into isolated rat hepatocytes

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Stereoselective inhibitory effect of flurbiprofen, ibuprofen and naproxen on human organic anion transporters hOAT1 and hOAT3.

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A mutation in the drug transporter gene ABCC2 associated with impaired methotrexate elimination

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Biological effects of folic acid antagonists with antineoplastic activity

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Effect of ketoprofen and its enantiomers on the renal disposition of methotrexate in the isolated perfused rat kidney.

1 reference

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Interactions of human organic anion transporters and human organic cation transporters with nonsteroidal anti-inflammatory drugs

1 reference

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21 January 2018

Stereoselective disposition of ibuprofen and flurbiprofen in rats.

1 reference

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Evaluation of the interaction between nonsteroidal anti-inflammatory drugs and methotrexate using human organic anion transporter 3-transfected cells

1 reference

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Acute renal failure due to concomitant action of methotrexate and indomethacin

1 reference

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21 January 2018

A functional study on polymorphism of the ATP-binding cassette transporter ABCG2: critical role of arginine-482 in methotrexate transport.

1 reference

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21 January 2018

Pharmacological aspects of chiral nonsteroidal anti-inflammatory drugs

1 reference

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21 January 2018

Stereoselective pharmacokinetics of flurbiprofen and formation of covalent adducts with plasma protein in adjuvant‐induced arthritic rats

1 reference

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21 January 2018

Quantitative evaluation of the drug-drug interactions between methotrexate and nonsteroidal anti-inflammatory drugs in the renal uptake process based on the contribution of organic anion transporters and reduced folate carrier

1 reference

https://api.crossref.org/works/10.1124/JPET.115.229104

21 January 2018

Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices

1 reference

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21 January 2018

Determination of mRNA Expression of Human UDP-Glucuronosyltransferases and Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction

1 reference

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21 January 2018

Stereoselective interactions of organic cations with the organic cation transporter in OK cells

1 reference

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21 January 2018

Disposition of flurbiprofen in man: influence of stereochemistry and age

1 reference

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21 January 2018

The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

1 reference

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21 January 2018

Pharmacokinetic interaction between high-dose methotrexate and amoxycillin

1 reference

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21 January 2018

Molecular aspects of renal anionic drug transport

1 reference

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21 January 2018

Glucuronidation of carboxylic acid containing compounds by UDP-glucuronosyltransferase isoforms

1 reference

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21 January 2018

Predictability of idiosyncratic drug toxicity risk for carboxylic acid-containing drugs based on the chemical stability of acyl glucuronide

1 reference

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21 January 2018

Expression Cloning and Characterization of a Novel Multispecific Organic Anion Transporter

1 reference

https://api.crossref.org/works/10.1124/JPET.115.229104

21 January 2018

Clinical Pharmacokinetics of Methotrexate1

1 reference

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21 January 2018

Contribution of multidrug resistance protein 2 (MRP2/ABCC2) to the renal excretion of p-aminohippurate (PAH) and identification of MRP4 (ABCC4) as a novel PAH transporter.

1 reference

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21 January 2018

In vitro analysis of human drug glucuronidation and prediction of in vivo metabolic clearance

1 reference

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Characterization of methotrexate transport and its drug interactions with human organic anion transporters

1 reference

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The different effects of itraconazole on the pharmacokinetics of fexofenadine enantiomers

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Clinical and pharmacokinetic evidence of a life-threatening interaction between methotrexate and ketoprofen

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Pharmacokinetic interaction between high-dose methotrexate and oxacillin.

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The effects of a salicylate, ibuprofen, and naproxen on the disposition of methotrexate in patients with rheumatoid arthritis

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21 January 2018

Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter

1 reference

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Stereoselective uptake of beta-lactam antibiotics by the intestinal peptide transporter

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Understanding and managing methotrexate nephrotoxicity

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Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2).

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Identifiers

10.1124/JPET.115.229104

1 reference

Europe PubMed Central

PubMed publication ID

19 May 2018

http://europepmc.org/abstract/MED/26659924

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 May 2018

http://europepmc.org/abstract/MED/26659924

ResearchGate publication ID

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