Promiscuous, Multi-Target Lupane-Type Triterpenoids Inhibits Wild Type and Drug Resistant HIV-1 Replication Through the Interference With Several Targets. (Q53688749)

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scientific article published on 18 April 2018

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English	Promiscuous, Multi-Target Lupane-Type Triterpenoids Inhibits Wild Type and Drug Resistant HIV-1 Replication Through the Interference With Several Targets.	scientific article published on 18 April 2018

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scholarly article

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25 March 2020

Promiscuous, Multi-Target Lupane-Type Triterpenoids Inhibits Wild Type and Drug Resistant HIV-1 Replication Through the Interference With Several Targets (English)

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25 March 2020

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25 March 2020

author name string

Luis M Bedoya

1

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25 March 2020

Manuela Beltrán

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25 March 2020

Javier García-Pérez

3

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25 March 2020

Patricia Obregón-Calderón

4

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25 March 2020

Oliver Callies

5

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25 March 2020

Ignacio A Jímenez

6

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25 March 2020

Isabel L Bazzocchi

7

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18 April 2018

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25 March 2020

Frontiers in Pharmacology

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25 March 2020

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25 March 2020

358

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25 March 2020

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Creative Commons Attribution 4.0 International

18 April 2018

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April 2022 Public Data File from Crossref

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1 reference

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Identification and Characterization of BMS-955176, a Second-Generation HIV-1 Maturation Inhibitor with Improved Potency, Antiviral Spectrum, and Gag Polymorphic Coverage.

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Filtering promiscuous compounds in early drug discovery: is it a good idea?

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22 May 2018

Isolation, Structural Modification, and HIV Inhibition of Pentacyclic Lupane-Type Triterpenoids from Cassine xylocarpa and Maytenus cuzcoina.

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Compound promiscuity: what can we learn from current data?

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Synthesis and biological evaluation of a new derivative of bevirimat that targets the Gag CA-SP1 cleavage site

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Olean-18-ene triterpenoids from Celastraceae species inhibit HIV replication targeting NF-kB and Sp1 dependent transcription.

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HIV-1 protease inhibitor mutations affect the development of HIV-1 resistance to the maturation inhibitor bevirimat.

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A single polymorphism in HIV-1 subtype C SP1 is sufficient to confer natural resistance to the maturation inhibitor bevirimat

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Rapid access to new bioconjugates of betulonic acid via click chemistry.

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Designed multiple ligands: an emerging anti-HIV drug discovery paradigm

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Anti-AIDS agents. 78. Design, synthesis, metabolic stability assessment, and antiviral evaluation of novel betulinic acid derivatives as potent anti-human immunodeficiency virus (HIV) agents

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3-O-(3',3'-dimethysuccinyl) betulinic acid inhibits maturation of the human immunodeficiency virus type 1 Gag precursor assembled in vitro

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22 May 2018

Designed multiple ligands. An emerging drug discovery paradigm

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Chemistry, biological activity, and chemotherapeutic potential of betulinic acid for the prevention and treatment of cancer and HIV infection

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PA-457: A potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processing

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Analysis of early human immunodeficiency virus type 1 DNA synthesis by use of a new sensitive assay for quantifying integrated provirus

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Role of human immunodeficiency virus (HIV) type 1 envelope in the anti-HIV activity of the betulinic acid derivative IC9564

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Identifiers

10.3389/FPHAR.2018.00358

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29720939 AND SRC:MED&resulttype=core&format=json

25 March 2020

PMC publication ID

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25 March 2020

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Europe PubMed Central

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25 March 2020

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