Synthesis and biological evaluation of new inhibitors of UDP-Galf transferase--a key enzyme in M. tuberculosis cell wall biosynthesis. (Q53635604)

16 May 2018

title

Synthesis and biological evaluation of new inhibitors of UDP-Galf transferase--a key enzyme in M. tuberculosis cell wall biosynthesis. (English)

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Mycobacterium tuberculosis

main subject

tuberculosis

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3

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Gurdyal Besra

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author name string

Sylvaine Cren

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Sudagar S Gurcha

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Neil R Thomas

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publication date

9 August 2004

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Organic and Biomolecular Chemistry

published in

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volume

2

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issue

17

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page(s)

2418-2420

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Cell wall core galactofuran synthesis is essential for growth of mycobacteria

cites work

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UDP-galactopyranose mutase has a novel structure and mechanism

21 January 2018

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Potentiometric analysis of UDP-galactopyranose mutase: stabilization of the flavosemiquinone by substrate

21 January 2018

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Reconstitution of UDP-galactopyranose mutase with 1-deaza-FAD and 5-deaza-FAD: analysis and mechanistic implications

21 January 2018

1 reference

Synthesis and inhibition properties of conformational probes for the mutase-catalyzed UDP-galactopyranose/furanose interconversion.

21 January 2018

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A unique catalytic mechanism for UDP-galactopyranose mutase

21 January 2018

1 reference

Efficient synthesis of a nucleoside-diphospho-exo-glycal displaying time-dependent inactivation of UDP-galactopyranose mutase

21 January 2018

1 reference

Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase

21 January 2018

1 reference

Recent developments of transition-state analogue glycosidase inhibitors of non-natural product origin

21 January 2018

1 reference

Synthesis of an aza analogue of 2-deoxy-D-ribofuranose and its homologues.

21 January 2018

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Intercalating nucleic acids (INAs) with insertion of N-(pyren-1-ylmethyl)-(3R,4R)-4-(hydroxymethyl)pyrrolidin-3-ol. DNA (RNA) duplex and DNA three-way junction stabilities

21 January 2018

1 reference

Studies on (beta,1-->5) and (beta,1-->6) linked octyl Gal(f) disaccharides as substrates for mycobacterial galactosyltransferase activity.

21 January 2018

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Design, synthesis and biological evaluation of iminosugar-based glycosyltransferase inhibitors

21 January 2018

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Carbohydrate mimetics-based glycosyltransferase inhibitors

21 January 2018

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Drug targeting Mycobacterium tuberculosis cell wall synthesis: development of a microtiter plate-based screen for UDP-galactopyranose mutase and identification of an inhibitor from a uridine-based library

21 January 2018

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32 Concentrations of binding protein and labeled analyte that are appropriate for measuring at any analyte concentration range in radioimmunoassays

21 January 2018

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Inhibition of UDP-Gal Mutase and Mycobacterial Galactan Biosynthesis by Pyrrolidine Analogues of Galactofuranose

21 January 2018

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1-Azaribofuranoside analogues as designed inhibitors of purine nucleoside phosphorylase. Synthesis and biological evaluation

21 January 2018

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31 May 2024

https://opencitations.net/index/api/v1/citations/10.3891/ACTA.CHEM.SCAND.52-1214

Identifiers

DOI

10.1039/B411554F

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16 May 2018

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