Targeting inhibition of K-ras enhances Ad.mda-7-induced growth suppression and apoptosis in mutant K-ras colorectal cancer cells. (Q53603958)

16 May 2018

title

Targeting inhibition of K-ras enhances Ad.mda-7-induced growth suppression and apoptosis in mutant K-ras colorectal cancer cells. (English)

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16 May 2018

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Lebedeva IV

1

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16 May 2018

Su ZZ

2

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16 May 2018

Emdad L

3

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16 May 2018

Kolomeyer A

4

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16 May 2018

Sarkar D

5

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16 May 2018

Kitada S

6

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16 May 2018

Waxman S

7

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16 May 2018

Reed JC

8

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16 May 2018

Fisher PB

9

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16 May 2018

language of work or name

English

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publication date

21 August 2006

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16 May 2018

published in

Oncogene

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16 May 2018

volume

26

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16 May 2018

issue

5

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16 May 2018

page(s)

733-744

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16 May 2018

Blocking oncogenic Ras signaling for cancer therapy

cites work

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Induction of apoptosis and G2/M arrest by infection with replication-deficient adenovirus at high multiplicity of infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

The mode of action of Y13-259 scFv fragment intracellularly expressed in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

mda-7 gene transfer sensitizes breast carcinoma cells to chemotherapy, biologic therapies and radiotherapy: correlation with expression of bcl-2 family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

MDA-7/IL-24 is a unique cytokine--tumor suppressor in the IL-10 family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

A genetic model for colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Bcl-2 associates with the ras-related protein R-ras p23

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Is mda-7/IL-24 a "magic bullet" for cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Molecular target-based therapy of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Bcl-2 and Bcl-x(L) differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

mda-7/IL-24: exploiting cancer's Achilles' heel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

RPR-115135, a farnesyltransferase inhibitor, increases 5-FU- cytotoxicity in ten human colon cancer cell lines: role of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Targeted virus replication plus immunotherapy eradicates primary and distant pancreatic tumors in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

The ras oncogenes increase the intrinsic resistance of NIH 3T3 cells to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Ionizing radiation enhances therapeutic activity of mda-7/IL-24: overcoming radiation- and mda-7/IL-24-resistance in prostate cancer cells overexpressing the antiapoptotic proteins bcl-xL or bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Subtraction hybridization identifies a transformation progression-associated gene PEG -3 with sequence homology to a growth arrest and DNA damage-inducible gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Advanced colorectal cancer: current treatment and nursing management with economic considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Genetic alterations during colorectal-tumor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Cancer. Addiction to oncogenes--the Achilles heal of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

mda-7(IL-24) Inhibits Growth and Enhances Radiosensitivity of Glioma Cells In Vitro via JNK Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Proof without prejudice: use of the Kolmogorov-Smirnov test for the analysis of histograms from flow systems and other sources

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Potent antitumor activity of oncolytic adenovirus expressing mda-7/IL-24 for colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Prevalence of ras gene mutations in human colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

Suppression of Ki-ras p21 levels leading to growth inhibition of pancreatic cancer cell lines with Ki-ras mutation but not those without Ki-ras mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

7 January 2021

Re: Blocking Oncogenic Ras Signaling for Cancer Therapy

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

7 January 2021

Clinical and local biological effects of an intratumoral injection of mda-7 (IL24; INGN 241) in patients with advanced carcinoma: a phase I study

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

7 January 2021

Growth inhibition of human pancreatic cancer cell lines by anti-sense oligonucleotides specific to mutated K-ras genes

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

7 January 2021

A combinatorial approach for selectively inducing programmed cell death in human pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

7 January 2021

Activation of the K-ras oncogene in colorectal neoplasms is associated with decreased apoptosis

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1209813

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209813

1 reference

16 May 2018

release_tkl7rgrj2rf7bgy76qpf67qmiq

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tkl7rgrj2rf7bgy76qpf67qmiq

24 November 2022

mapped directly with Wikidata item

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16 May 2018