NSC126188, a piperazine alkyl derivative, induces apoptosis via upregulation of RhoB in HeLa cells. (Q53472036)

14 May 2018

title

NSC126188, a piperazine alkyl derivative, induces apoptosis via upregulation of RhoB in HeLa cells. (English)

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14 May 2018

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Bo-Kyung Kim

1

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14 May 2018

Dong-Myung Kim

2

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14 May 2018

Kyung-Sook Chung

3

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14 May 2018

Song-Kyu Park

4

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14 May 2018

Shin-Jung Choi

5

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14 May 2018

Alexander Song

6

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14 May 2018

Kiho Lee

7

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14 May 2018

Chang-Woo Lee

8

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14 May 2018

Kyung-Bin Song

9

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14 May 2018

Gyoonhee Han

10

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14 May 2018

Julian Simon

11

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14 May 2018

Hwan Mook Kim

12

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14 May 2018

Misun Won

13

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14 May 2018

publication date

30 April 2010

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14 May 2018

Investigational New Drugs

published in

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14 May 2018

volume

29

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issue

5

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14 May 2018

page(s)

853-860

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Rho GTPases: promising cellular targets for novel anticancer drugs

cites work

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

Actin' up: RhoB in cancer and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

RhoB and the mammalian Diaphanous-related formin mDia2 in endosome trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

EGFR, ErbB2 and Ras but not Src suppress RhoB expression while ectopic expression of RhoB antagonizes oncogene-mediated transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

Akt mediates Ras downregulation of RhoB, a suppressor of transformation, invasion, and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

Transcriptional activation of the small GTPase gene rhoB by genotoxic stress is regulated via a CCAAT element

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

Histone deacetylase 1 represses the small GTPase RhoB expression in human nonsmall lung carcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

Identification of small molecules inducing apoptosis by cell-based assay using fission yeast deletion mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

Cerulenin-mediated apoptosis is involved in adenine metabolic pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

A novel benzimidazole analogue inhibits the hypoxia-inducible factor (HIF)-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

RhoB induces apoptosis via direct interaction with TNFAIP1 in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

TMEM16A confers receptor-activated calcium-dependent chloride conductance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

A novel stereo-selective sulfonylurea, 1-[1-(4-aminobenzoyl)-2,3-dihydro-1H-indol-6-sulfonyl]-4-phenyl-imidazolidin-2-one, has antitumor efficacy in in vitro and in vivo tumor models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

The control of septum formation in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

Novel Rho GTPase involved in cytokinesis and cell wall integrity in the fission yeast Schizosaccharomyces pombe

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

Schizosaccharomyces pombe cells lacking the Ran-binding protein Hba1 show a multidrug resistance phenotype due to constitutive nuclear accumulation of Pap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

mDia function is critical for the cell suicide program triggered by farnesyl transferase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

Farnesyltransferase inhibitors induce DNA damage via reactive oxygen species in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

Increase of RhoB in gamma-radiation-induced apoptosis is regulated by c-Jun N-terminal kinase in Jurkat T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

Farnesyl transferase inhibitors: one target may be found in another

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S10637-010-9433-3

Rapid induction of apoptosis by combination of flavopiridol and tumor necrosis factor (TNF)-alpha or TNF-related apoptosis-inducing ligand in human cancer cell lines.

21 January 2018

1 reference

12 December 2020

RhoB in cancer suppression

1 reference

12 December 2020

Both farnesylated and geranylgeranylated RhoB inhibit malignant transformation and suppress human tumor growth in nude mice

1 reference

12 December 2020

Dma1 prevents mitotic exit and cytokinesis by inhibiting the septation initiation network (SIN)

1 reference

12 December 2020

The small GTPase Rho3 and the diaphanous/formin For3 function in polarized cell growth in fission yeast

1 reference

12 December 2020

Suppression of rho B expression in invasive carcinoma from head and neck cancer patients

1 reference

12 December 2020

10.1007/S10637-010-9433-3

Identifiers

DOI

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14 May 2018

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14 May 2018