Aberrant cell cycle progression contributes to the early-stage accelerated carcinogenesis in transgenic epidermis expressing the dominant negative TGFbetaRII. (Q53406731)

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English	Aberrant cell cycle progression contributes to the early-stage accelerated carcinogenesis in transgenic epidermis expressing the dominant negative TGFbetaRII.	scientific article

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10951568

Aberrant cell cycle progression contributes to the early-stage accelerated carcinogenesis in transgenic epidermis expressing the dominant negative TGFbetaRII. (English)

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10951568

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Go C

1

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10951568

He W

2

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10951568

Zhong L

3

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Europe PubMed Central

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14 May 2018

http://europepmc.org/abstract/MED/10951568

Li P

4

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Europe PubMed Central

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14 May 2018

http://europepmc.org/abstract/MED/10951568

Huang J

5

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Europe PubMed Central

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14 May 2018

http://europepmc.org/abstract/MED/10951568

Brinkley BR

6

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14 May 2018

http://europepmc.org/abstract/MED/10951568

Wang XJ

7

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14 May 2018

http://europepmc.org/abstract/MED/10951568

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1 July 2000

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14 May 2018

http://europepmc.org/abstract/MED/10951568

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Europe PubMed Central

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14 May 2018

http://europepmc.org/abstract/MED/10951568

19

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14 May 2018

http://europepmc.org/abstract/MED/10951568

32

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10951568

3623-3631

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Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10951568

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Biochemical evidence for the autophosphorylation and transphosphorylation of transforming growth factor beta receptor kinases

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Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-beta activities.

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TGF-beta-receptor-mediated signaling

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p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

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Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15

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neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice

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Mutations of the transforming growth factor-beta type II receptor gene and genomic instability in hereditary nonpolyposis colorectal cancer

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HNPCC associated with germline mutation in the TGF-β type II receptor gene

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Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

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c-myc and pRB: role in TGF-beta 1 inhibition of keratinocyte proliferation

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Transforming growth factor beta targeted inactivation of cyclin E:cyclin-dependent kinase 2 (Cdk2) complexes by inhibition of Cdk2 activating kinase activity

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p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

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Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis

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Signaling activity of transforming growth factor beta type II receptors lacking specific domains in the cytoplasmic region

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Identifiers

10.1038/SJ.ONC.1203701

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10951568

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/10951568

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