Mitosis is not a key target of microtubule agents in patient tumors. (Q53271035)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21283127 AND SRC:MED&resulttype=core&format=json

21 January 2020

review article

1 reference

title

Mitosis is not a key target of microtubule agents in patient tumors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21283127 AND SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

Edina Komlodi-Pasztor

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21283127 AND SRC:MED&resulttype=core&format=json

21 January 2020

Dan Sackett

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21283127 AND SRC:MED&resulttype=core&format=json

21 January 2020

language of work or name

English

0 references

publication date

1 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21283127 AND SRC:MED&resulttype=core&format=json

Nature Reviews Clinical Oncology

21 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21283127 AND SRC:MED&resulttype=core&format=json

21 January 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21283127 AND SRC:MED&resulttype=core&format=json

21 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21283127 AND SRC:MED&resulttype=core&format=json

21 January 2020

page(s)

244-250

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21283127 AND SRC:MED&resulttype=core&format=json

How do microtubule-targeted drugs work? An overview

21 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Microtubule organizing centers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Moving on to the cargo problem of microtubule-dependent motors in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Basal bodies platforms for building cilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Head-to-tail polymerization of microtubules in vitro. Electron microscope analysis of seeded assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Polarity of microtubules nucleated by centrosomes and chromosomes of Chinese hamster ovary cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Kinesin superfamily motor proteins and intracellular transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Regulators of the cytoplasmic dynein motor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Regulation of mitosis via mitotic kinases: new opportunities for cancer management

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Target validation and biomarker identification in oncology : the example of aurora kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Polo-like kinase inhibitors: an emerging opportunity for cancer therapeutics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Polo and Aurora kinases: lessons derived from chemical biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

K858, a novel inhibitor of mitotic kinesin Eg5 and antitumor agent, induces cell death in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Targeted anti-mitotic therapies: can we improve on tubulin agents?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

On the role of aurora-A in centrosome function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Polo-like kinases: a team in control of the division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Functional dynamics of Polo-like kinase 1 at the centrosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Kinesin motor proteins as targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Targeting the kinesin spindle protein: basic principles and clinical implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Progress on kinesin spindle protein inhibitors as anti-cancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Relationships between tumor responsiveness, vincristine pharmacokinetics and arrest of mitosis in human tumor xenografts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Length of mitotic arrest induced by microtubule-stabilizing drugs determines cell death after mitotic exit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Is cell death a critical end point for anticancer therapies or is cytostasis sufficient?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Neutrophil kinetics in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Phase I pharmacokinetic and pharmacodynamic study of the aurora kinase inhibitor danusertib in patients with advanced or metastatic solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Phase I dose escalation and pharmacokinetic study of BI 2536, a novel Polo-like kinase 1 inhibitor, in patients with advanced solid tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

BRCA1 is associated with the centrosome during mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

A microtubule-facilitated nuclear import pathway for cancer regulatory proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Tubulin-Targeting Chemotherapy Impairs Androgen Receptor Activity in Prostate Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Microtubules and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Signal transduction pathways of taxanes-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Mode of action of docetaxel - a basis for combination with novel anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

From signaling pathways to microtubule dynamics: the key players.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Taxol induces oxidative neuronal cell death by enhancing the activity of NADPH oxidase in mouse cortical cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Non-anti-mitotic concentrations of taxol reduce breast cancer cell invasiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Tumour targeting by microtubule-depolymerizing vascular disrupting agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Targeting microtubules to inhibit angiogenesis and disrupt tumour vasculature: implications for cancer treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Prospective study of paclitaxel-induced peripheral neuropathy with quantitative sensory testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Evolution of neuropathy and myopathy during intensive vincristine/corticosteroid chemotherapy for non-hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Peripheral neuropathy: a persisting challenge in paclitaxel-based regimes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Taxol neuropathy. Electrodiagnostic and sural nerve biopsy findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Peripheral nerve damage associated with administration of taxanes in patients with cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Rapid reformation of the thick chromosome fiber upon completion of RNA synthesis at the Balbiani ring genes in Chironomus tentans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Doxorubicin: the good, the bad and the ugly effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Camptothecins and Topoisomerase I; A Foot in the Door. Targeting the Genome Beyond Topoisomerase I with Camptothecins and Novel Anticancer Drugs; Importance of DNA Replication, Repair and Cell Cycle Checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

A non-radioactive sensitive assay to measure 5-fluorouracil incorporation into DNA of solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

The price of innovation: new estimates of drug development costs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Estimating the cost of new drug development: is it really 802 million dollars?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Kinetics of mitotic arrest and apoptosis in murine mammary and ovarian tumors treated with taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Phase II Trial of Ixabepilone, an Epothilone B Analog, in Patients With Metastatic Breast Cancer Previously Untreated With Taxanes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

p53 is associated with cellular microtubules and is transported to the nucleus by dynein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Subcellular localization of the BRCA1 gene product in mitotic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Paclitaxel-induced neuropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

MK-0457, a novel kinase inhibitor, is active in patients with chronic myeloid leukemia or acute lymphocytic leukemia with the T315I BCR-ABL mutation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/NRCLINONC.2010.228

Beyond taxanes: a review of novel agents that target mitotic tubulin and microtubules, kinases, and kinesins.

31 March 2020

1 reference

12 December 2020

Antiangiogenic activity of paclitaxel is associated with its cytostatic effect, mediated by the initiation but not completion of a mitochondrial apoptotic signaling pathway

1 reference

12 December 2020

Molecular Mechanisms and Function of the Spindle Checkpoint, a Guardian of the Chromosome Stability

1 reference

12 December 2020

THE RELATIONSHIP OF THE CELL CYCLE TO TUMOR GROWTH AND CONTROL OF CELL DIVISION: A REVIEW.

1 reference

12 December 2020

Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature

1 reference

12 December 2020

In vitro determination of thymidine-3H labeling index in human solid tumors

1 reference

12 December 2020

10.1038/NRCLINONC.2010.228

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21283127 AND SRC:MED&resulttype=core&format=json

21 January 2020

1 reference