Direct anti-cancer effect of oncostatin M on chondrosarcoma. (Q53265964)

12 May 2018

title

Direct anti-cancer effect of oncostatin M on chondrosarcoma. (English)

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2

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Frédéric Blanchard

13

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Emmanuelle David

object named as

Emmanuelle David

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Carl D Richards

object named as

Carl D Richards

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Dominique Heymann

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object named as

Dominique Heymann

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Bénédicte Brounais

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Anne Riet

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Céline Charrier

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Séverine Battaglia

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François Gouin

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Stéphanie Ponsolle

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Ronan Le Bot

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Françoise Rédini

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language of work or name

English

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publication date

6 January 2011

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International Journal of Cancer

published in

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volume

128

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issue

8

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page(s)

1822-1835

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Emerging pathways in the development of chondrosarcoma of bone and implications for targeted treatment

cites work

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Towards a new understanding and classification of chondrogenic neoplasias of the skeleton--biochemistry and cell biology of chondrosarcoma and its variants

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The clinical approach towards chondrosarcoma

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Cartilage tumours and bone development: molecular pathology and possible therapeutic targets.

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COX-2 expression in chondrosarcoma: a role for celecoxib treatment?

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Central chondrosarcoma progression is associated with pRb pathway alterations: CDK4 down-regulation and p16 overexpression inhibit cell growth in vitro

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Preclinical evidence that use of TRAIL in Ewing's sarcoma and osteosarcoma therapy inhibits tumor growth, prevents osteolysis, and increases animal survival

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A chondrogenic gene expression signature in mesenchymal stem cells is a classifier of conventional central chondrosarcoma.

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Endochondral ossification: how cartilage is converted into bone in the developing skeleton.

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SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification

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Role of matrix metalloproteinase 13 in both endochondral and intramembranous ossification during skeletal regeneration

21 January 2018

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Murine and chicken chondrocytes regulate osteoclastogenesis by producing RANKL in response to BMP2

21 January 2018

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Expression profile of genes related to osteoclastogenesis in mouse growth plate and articular cartilage.

21 January 2018

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The dual role of IL-6-type cytokines on bone remodeling and bone tumors

21 January 2018

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Relationship between responsiveness of cancer cells to Oncostatin M and/or IL-6 and survival of stage III melanoma patients treated with tumour-infiltrating lymphocytes

21 January 2018

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Downregulation of osteoblast markers and induction of the glial fibrillary acidic protein by oncostatin M in osteosarcoma cells require PKCdelta and STAT3.

21 January 2018

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Human interleukin for DA cells/leukemia inhibitory factor and oncostatin M enhance membrane expression of intercellular adhesion molecule-1 on melanoma cells but not the shedding of its soluble form.

21 January 2018

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A model of inflammatory arthritis highlights a role for oncostatin M in pro-inflammatory cytokine-induced bone destruction via RANK/RANKL

21 January 2018

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IL-6, leukemia inhibitory factor, and oncostatin M stimulate bone resorption and regulate the expression of receptor activator of NF-kappa B ligand, osteoprotegerin, and receptor activator of NF-kappa B in mouse calvariae

21 January 2018

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A novel distal enhancer mediates cytokine induction of mouse RANKl gene expression

21 January 2018

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Oncostatin-M induction of vascular endothelial growth factor expression in astroglioma cells

21 January 2018

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Interleukin-1 in combination with oncostatin M up-regulates multiple genes in chondrocytes: implications for cartilage destruction and repair

21 January 2018

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Oncostatin M induces bone loss and sensitizes rat osteosarcoma to the antitumor effect of Midostaurin in vivo

21 January 2018

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Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells

21 January 2018

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Sensitization of osteosarcoma cells to apoptosis by oncostatin M depends on STAT5 and p53.

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Long term oncostatin M treatment induces an osteocyte-like differentiation on osteosarcoma and calvaria cells

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Osteosarcoma originates from mesenchymal stem cells in consequence of aneuploidization and genomic loss of Cdkn2.

21 January 2018

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Zoledronic acid slows down rat primary chondrosarcoma development, recurrent tumor progression after intralesional curretage and increases overall survival.

21 January 2018

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Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

21 January 2018

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Adenovirus vector expressing mouse oncostatin M induces acute-phase proteins and TIMP-1 expression in vivo in mice.

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A new human chondrosarcoma cell line (OUMS-27) that maintains chondrocytic differentiation

21 January 2018

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Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort

21 January 2018

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Interleukin-6 and transforming growth factor-beta synergistically stimulate chondrosarcoma cell proliferation

21 January 2018

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Defective activations of STAT3 Ser727 and PKC isoforms lead to oncostatin M resistance in metastatic melanoma cells

21 January 2018

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Interferon-alpha delays S-phase progression in human hepatocellular carcinoma cells via inhibition of specific cyclin-dependent kinases.

21 January 2018

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Divergent roles of STAT1 and STAT5 in malignancy as revealed by gene disruptions in mice

21 January 2018

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FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway

21 January 2018

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Overexpression of FGFR3, Stat1, Stat5 and p21Cip1 correlates with phenotypic severity and defective chondrocyte differentiation in FGFR3-related chondrodysplasias

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Interleukin-6 dependent induction of the cyclin dependent kinase inhibitor p21WAF1/CIP1 is lost during progression of human malignant melanoma.

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Anin VitroModel to Study Mesenchymal– Epithelial Transformation

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Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways

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Oncostatin M induces angiogenesis and cartilage degradation in rheumatoid arthritis synovial tissue and human cartilage cocultures

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Identifiers

DOI

10.1002/IJC.25776

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12 May 2018

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12 May 2018