RASSF1A inhibits estrogen receptor alpha expression and estrogen-independent signalling: implications for breast cancer development. (Q53190494)

12 May 2018

title

RASSF1A inhibits estrogen receptor alpha expression and estrogen-independent signalling: implications for breast cancer development. (English)

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12 May 2018

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4

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author name string

S Thaler

series ordinal

1

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12 May 2018

M Schmidt

series ordinal

2

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12 May 2018

A Schad

series ordinal

3

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12 May 2018

language of work or name

English

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publication date

23 January 2012

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12 May 2018

published in

Oncogene

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12 May 2018

volume

31

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issue

47

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12 May 2018

page(s)

4912-4922

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12 May 2018

Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors.

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Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter

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Integration of the extranuclear and nuclear actions of estrogen

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Proximal events in signaling by plasma membrane estrogen receptors

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Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase

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PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells

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Breast cancer risk in usual ductal hyperplasia is defined by estrogen receptor-alpha and Ki-67 expression

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Abnormal regulation of the oestrogen receptor in benign breast lesions

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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

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17beta-estradiol inhibits apoptosis in MCF-7 cells, inducing bcl-2 expression via two estrogen-responsive elements present in the coding sequence.

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Overexpression of c-Myc and Bcl-2 during progression and distant metastasis of hormone-treated breast cancer

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Complementation by BCL2 and C-HA-RAS oncogenes in malignant transformation of rat embryo fibroblasts

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Regulation of the Expression of Cyclin-Dependent Kinase Inhibitor p21 by E2A and Id Proteins

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Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

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Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response

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Coupling of Cell Growth Control and Apoptosis Functions of Id Proteins

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Transfection of v-rasH DNA into MCF-7 human breast cancer cells bypasses dependence on estrogen for tumorigenicity

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RASSF1A mediates p21Cip1/Waf1-dependent cell cycle arrest and senescence through modulation of the Raf-MEK-ERK pathway and inhibition of Akt.

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Altered target gene regulation controlled by estrogen receptor-alpha concentration

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Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer.

21 January 2018

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Caveolin-1 mutations in human breast cancer: functional association with estrogen receptor alpha-positive status

21 January 2018

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miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer

21 January 2018

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Identification of a novel estrogen receptor beta1 binding partner, inhibitor of differentiation-1, and role of ERbeta1 in human breast cancer cells

21 January 2018

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ERs associate with and regulate the production of caveolin: implications for signaling and cellular actions

21 January 2018

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Regulation of Raf-Akt Cross-talk

21 January 2018

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Integrative genomic approaches identify IKBKE as a breast cancer oncogene

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

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Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity

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Mice expressing myrAKT1 in the mammary gland develop carcinogen-induced ER-positive mammary tumors that mimic human breast cancer

21 January 2018

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https://api.crossref.org/works/10.1038/ONC.2011.658

Distinct hypermethylation profile of primary breast cancer is associated with sentinel lymph node metastasis

21 January 2018

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https://api.crossref.org/works/10.1038/ONC.2011.658

Mammary gland development in adult mice requires epithelial and stromal estrogen receptor alpha

31 March 2020

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https://api.crossref.org/works/10.1038/ONC.2011.658

Oestrogen receptor expression in the normal and pre-cancerous breast

31 March 2020

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https://api.crossref.org/works/10.1038/ONC.2011.658

Estrogen receptor expression in benign breast epithelium and breast cancer risk

31 March 2020

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https://api.crossref.org/works/10.1038/ONC.2011.658

Low oestrogen receptor alpha expression in normal breast tissue underlies low breast cancer incidence in Japan

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.658

Expression of steroid hormone receptors, their regulated proteins, and bcl-2 protein in myofibroblastoma of the breast

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.658

Expression of Bcl-2, but not Bax, correlates with estrogen receptor status and tumor proliferation in invasive breast carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.658

Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.658

Src is an initial target of sex steroid hormone action

31 March 2020

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.658

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.658

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12 May 2018

Dimensions Publication ID

1021372811

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12 May 2018