Uric acid induces fat accumulation via generation of endoplasmic reticulum stress and SREBP-1c activation in hepatocytes. (Q53028338)

10 May 2018

title

Uric acid induces fat accumulation via generation of endoplasmic reticulum stress and SREBP-1c activation in hepatocytes. (English)

1 reference

10 May 2018

main subject

endoplasmic reticulum

0 references

author name string

Yea-Jin Choi

1

1 reference

10 May 2018

Hyun-Soo Shin

2

1 reference

10 May 2018

Hack Sun Choi

3

1 reference

10 May 2018

Joo-Won Park

4

1 reference

10 May 2018

Inho Jo

5

1 reference

10 May 2018

Eok-Soo Oh

6

1 reference

10 May 2018

Kang-Yo Lee

7

1 reference

10 May 2018

Byung-Hoon Lee

8

1 reference

10 May 2018

Richard J Johnson

9

1 reference

10 May 2018

Duk-Hee Kang

10

1 reference

10 May 2018

publication date

11 August 2014

1 reference

10 May 2018

published in

Laboratory Investigation

1 reference

10 May 2018

volume

94

1 reference

10 May 2018

issue

10

1 reference

10 May 2018

page(s)

1114-1125

1 reference

10 May 2018

Nonalcoholic fatty liver disease

cites work

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Recent advances in nonalcholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Endoplasmic reticulum stress in nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Endoplasmic reticulum stress is involved in hepatic SREBP-1c activation and lipid accumulation in fructose-fed mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Changes in hepatic gene expression upon oral administration of taurine-conjugated ursodeoxycholic acid in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Elevated serum uric acid levels are associated with non-alcoholic fatty liver disease independently of metabolic syndrome features in the United States: Liver ultrasound data from the National Health and Nutrition Examination Survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Serum uric acid levels predict incident nonalcoholic fatty liver disease in healthy Korean men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Uric acid stimulates fructokinase and accelerates fructose metabolism in the development of fatty liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Effects of nutrients and hormones on transcriptional and post-transcriptional regulation of acetyl-CoA carboxylase in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Ablation of very long acyl chain sphingolipids causes hepatic insulin resistance in mice due to altered detergent-resistant membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Ablation of ceramide synthase 2 causes chronic oxidative stress due to disruption of the mitochondrial respiratory chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Regulation of hepatic lipogenesis by the transcription factor XBP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid synthesis in liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Cross talk between mitochondria and NADPH oxidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.2014.98

Effects of nutrients and insulin on transcriptional and post-transcriptional regulation of glucose-6-phosphate dehydrogenase synthesis in rat liver

21 January 2018

1 reference

12 December 2020

Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formation

1 reference

12 December 2020

Hypouricemic therapy: A novel potential therapeutic option for nonalcoholic fatty liver disease

1 reference

12 December 2020

Dietary regulation of stearoyl-CoA desaturase 1 gene expression in mouse liver

1 reference

12 December 2020

10.1038/LABINVEST.2014.98

Identifiers

DOI

1 reference

10 May 2018

release_cjfvl32sjrbhdphroygky3glpm

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/cjfvl32sjrbhdphroygky3glpm

24 November 2022

mapped directly with Wikidata item

1 reference

10 May 2018