Isoliquiritigenin as a cause of DNA damage and inhibitor of ataxia-telangiectasia mutated expression leading to G2/M phase arrest and apoptosis in oral squamous cell carcinoma. (Q52976397)

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scientific article published on 10 January 2015

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English	Isoliquiritigenin as a cause of DNA damage and inhibitor of ataxia-telangiectasia mutated expression leading to G2/M phase arrest and apoptosis in oral squamous cell carcinoma.	scientific article published on 10 January 2015

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/25580586

Isoliquiritigenin as a cause of DNA damage and inhibitor of ataxia-telangiectasia mutated expression leading to G2/M phase arrest and apoptosis in oral squamous cell carcinoma. (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/25580586

author name string

Shih-Min Hsia

1

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/25580586

Cheng-Chia Yu

2

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/25580586

Yin-Hua Shih

3

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/25580586

Michael Yuanchien Chen

4

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/25580586

Tong-Hong Wang

5

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/25580586

Yu-Ting Huang

6

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/25580586

Tzong-Ming Shieh

7

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/25580586

publication date

10 January 2015

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/25580586

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/25580586

38 Suppl 1

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/25580586

E360-71

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/25580586

Modifiable risk behaviors in patients with head and neck cancer

1 reference

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Head and neck cancer incidence trends in young Americans, 1973-1997, with a special analysis for tongue cancer

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Modulations of the Bcl-2/Bax family were involved in the chemopreventive effects of licorice root (Glycyrrhiza uralensis Fisch) in MCF-7 human breast cancer cell

1 reference

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21 January 2018

Isoliquiritigenin, a chalcone compound, enhances spontaneous inhibitory postsynaptic response

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Shallot and licorice constituent isoliquiritigenin arrests cell cycle progression and induces apoptosis through the induction of ATM/p53 and initiation of the mitochondrial system in human cervical carcinoma HeLa cells.

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Novel herbal flavonoids promote apoptosis but differentially induce cell cycle arrest in human colon cancer cell

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Isoliquiritigenin (ISL) inhibits ErbB3 signaling in prostate cancer cells.

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Dietary compound isoliquiritigenin inhibits breast cancer neoangiogenesis via VEGF/VEGFR-2 signaling pathway

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Preparation of isoliquiritigenin-loaded nanostructured lipid carrier and the in vivo evaluation in tumor-bearing mice

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Isoliquiritigenin inhibits the proliferation and induces the apoptosis of human non-small cell lung cancer a549 cells

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Apoptosis induced by isoliquiritigenin in human gastric cancer MGC-803 cells

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Isoliquiritigenin induces apoptosis and cell cycle arrest through p53-dependent pathway in Hep G2 cells

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MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin

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Isoliquiritigenin inhibits tumor growth and protects the kidney and liver against chemotherapy-induced toxicity in a mouse xenograft model of colon carcinoma

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Mammalian target of rapamycin regulates isoliquiritigenin-induced autophagic and apoptotic cell death in adenoid cystic carcinoma cells

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Isoliquiritigenin induces apoptosis by depolarizing mitochondrial membranes in prostate cancer cells.

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21 January 2018

Cyclooxygenase-2 plays a suppressive role for induction of apoptosis in isoliquiritigenin-treated mouse colon cancer cells

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21 January 2018

Isoliquiritigenin induces G2 and M phase arrest by inducing DNA damage and by inhibiting the metaphase/anaphase transition.

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21 January 2018

Isoliquiritigen enhances the antitumour activity and decreases the genotoxic effect of cyclophosphamide.

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21 January 2018

Cytotoxic activity of isoliquiritigenin towards CCRF-CEM leukemia cells and its effect on DNA damage.

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Association of expression aberrances and genetic polymorphisms of lysyl oxidase with areca-associated oral tumorigenesis

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Association between the polymorphisms in exon 12 of hypoxia-inducible factor-1alpha and the clinicopathological features of oral squamous cell carcinoma

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In vitro response of human gingival epithelial S-G cells to resveratrol

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Evaluation physical characteristics and comparison antimicrobial and anti-inflammation potentials of dental root canal sealers containing hinokitiol in vitro.

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Lysyl oxidase and enhancement of cell proliferation and angiogenesis in oral squamous cell carcinoma.

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21 January 2018

Pharmacological inhibition of ATM by KU55933 stimulates ATM transcription

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miR-203 induces oxaliplatin resistance in colorectal cancer cells by negatively regulating ATM kinase

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21 January 2018

Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma

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21 January 2018

Inhibitory effects of isoliquiritigenin on the migration and invasion of human breast cancer cells

1 reference

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21 January 2018

ATM is down-regulated by N-Myc-regulated microRNA-421.

1 reference

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21 January 2018

Caspase-mediated cleavage of ATM during cisplatin-induced tubular cell apoptosis: inactivation of its kinase activity toward p53.

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21 January 2018

E-cadherin Regulates Anchorage-independent Growth and Survival in Oral Squamous Cell Carcinoma Cells

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21 January 2018

Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer

1 reference

https://api.crossref.org/works/10.1002/HED.24001

21 January 2018

Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion

1 reference

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21 January 2018

Dietary compound isoliquiritigenin targets GRP78 to chemosensitize breast cancer stem cells via β-catenin/ABCG2 signaling

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21 January 2018

New insights into p53 signaling and cancer cell response to DNA damage: implications for cancer therapy

1 reference

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21 January 2018

The combination of ionizing radiation and expression of a wild type p53 gene via recombinant adenovirus induced a prominent tumour suppressing effect in human oral squamous cell carcinoma

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21 January 2018

The chemoadjuvant potential of grape seed procyanidins on p53‐related cell death in oral cancer cells

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p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity

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DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis

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miR-421 induces cell proliferation and apoptosis resistance in human nasopharyngeal carcinoma via downregulation of FOXO4.

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MicroRNA-421 functions as an oncogenic miRNA in biliary tract cancer through down-regulating farnesoid X receptor expression

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Gastric juice microRNA-421 is a new biomarker for screening gastric cancer.

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Pharmacokinetics of isoliquiritigenin and its metabolites in rats: low bioavailability is primarily due to the hepatic and intestinal metabolism

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Isoliquiritigenin enhances radiosensitivity of HepG2 cells via disturbance of redox status

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p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

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Identifiers

10.1002/HED.24001

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/25580586

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 May 2018

http://europepmc.org/abstract/MED/25580586

ResearchGate publication ID

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