Molecular Design, Synthesis, and Evaluation of SNIPER(ER) That Induces Proteasomal Degradation of ERα. (Q52901738)

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29 February 2020

title

Molecular Design, Synthesis, and Evaluation of SNIPER(ER) That Induces Proteasomal Degradation of ERα (English)

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29 February 2020

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2

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29 February 2020

Norihito Shibata

series ordinal

5

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4

Nobumichi Ohoka

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3

Takayuki Hattori

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7

Mikihiko Naito

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29 February 2020

author name string

Keiichiro Okuhira

series ordinal

1

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29 February 2020

Masaaki Kurihara

series ordinal

6

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29 February 2020

language of work or name

English

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publication date

1 January 2016

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Methods in Molecular Biology

29 February 2020

published in

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volume

1366

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29 February 2020

page(s)

549-560

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Specific degradation of CRABP-II via cIAP1-mediated ubiquitylation induced by hybrid molecules that crosslink cIAP1 and the target protein.

29 February 2020

cites work

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Double protein knockdown of cIAP1 and CRABP-II using a hybrid molecule consisting of ATRA and IAPs antagonist.

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Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin-proteasome pathway

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Immunohistochemistry of estrogen and progesterone receptors reconsidered: experience with 5,993 breast cancers

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Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: results of a North American trial

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Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment

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Final overall survival: fulvestrant 500 mg vs 250 mg in the randomized CONFIRM trial

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Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy.

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Development of hybrid small molecules that induce degradation of estrogen receptor-alpha and necrotic cell death in breast cancer cells.

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A convenient synthesis of (Z)-4-hydroxy-N-desmethyltamoxifen (endoxifen).

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Measurement of protein using bicinchoninic acid

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21 January 2018

Identifiers

DOI

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29 February 2020

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