Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer's Disease. (Q52644610)

7 July 2018

title

Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer's Disease. (English)

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7 July 2018

7

George Perry

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7 July 2018

Tingxiang Yan

1

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7 July 2018

Luwen Wang

2

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7 July 2018

Ju Gao

3

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7 July 2018

Sandra L Siedlak

4

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7 July 2018

Mikayla L Huntley

5

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7 July 2018

Pichet Termsarasab

6

1 reference

7 July 2018

Shu G Chen

8

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7 July 2018

Xinglong Wang

9

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7 July 2018

publication date

1 January 2018

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7 July 2018

Journal of Alzheimer's Disease

published in

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7 July 2018

volume

63

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7 July 2018

issue

1

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7 July 2018

page(s)

157-165

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7 July 2018

Selective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cells.

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Phosphorylation of the amyloid β-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity.

10 July 2018

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Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases

10 July 2018

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RAB-10 Regulates Dendritic Branching by Balancing Dendritic Transport

10 July 2018

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RAB-10-Dependent Membrane Transport Is Required for Dendrite Arborization

10 July 2018

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Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes

10 July 2018

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Tau protein kinases: involvement in Alzheimer's disease

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Lgl1 Activation of Rab10 Promotes Axonal Membrane Trafficking Underlying Neuronal Polarization

10 July 2018

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Granulovacuolar degeneration (GVD) bodies of Alzheimer's disease (AD) resemble late-stage autophagic organelles

10 July 2018

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10 July 2018

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10 July 2018

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10 July 2018

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RAB-10 regulates glutamate receptor recycling in a cholesterol-dependent endocytosis pathway

10 July 2018

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Rab10 is involved in basolateral transport in polarized Madin-Darby canine kidney cells

10 July 2018

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Localization of LRRK2 to membranous and vesicular structures in mammalian brain

10 July 2018

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Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis

10 July 2018

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RAB-10 is required for endocytic recycling in the Caenorhabditis elegans intestine

10 July 2018

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A focus on the synapse for neuroprotection in Alzheimer disease and other dementias

10 July 2018

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Synaptic frailty and clathrin-mediated synaptic vesicle trafficking in Alzheimer's disease

10 July 2018

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Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

10 July 2018

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Alzheimer's disease-associated presenilin 2 interacts with DRAL, an LIM-domain protein

10 July 2018

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Presenilin structure, function and role in Alzheimer disease.

10 July 2018

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Presenilins and Alzheimer's disease: biological functions and pathogenic mechanisms

10 July 2018

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A monoclonal antibody that recognizes a phosphorylated epitope in Alzheimer neurofibrillary tangles, neurofilaments and tau proteins immunostains granulovacuolar degeneration

10 July 2018

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Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity

10 July 2018

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Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

10 July 2018

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Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience

10 July 2018

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Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils

13 August 2018

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Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson's disease.

13 August 2018

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LRRK2 variant associated with Alzheimer's disease.

13 August 2018

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Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila.

13 August 2018

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RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.

13 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6008156

Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12.

13 August 2018

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13 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/29562525

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29562525

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3233/JAD-180023

1 reference

7 July 2018

PMC publication ID

6008156

1 reference

7 July 2018

PubMed publication ID

29562525

1 reference

7 July 2018