Contextual determinants of TGFβ action in development, immunity and cancer. (Q52593116)

4 May 2018

http://europepmc.org/abstract/MED/29643418

title

Contextual determinants of TGFβ action in development, immunity and cancer. (English)

1 reference

4 May 2018

http://europepmc.org/abstract/MED/29643418

corrigendum / erratum

Publisher Correction: Contextual determinants of TGFβ action in development, immunity and cancer

0 references

author

Joan Massagué Solé

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29643418 AND SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Charles J David

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29643418 AND SRC:MED&resulttype=core&format=json

10 June 2020

publication date

11 April 2018

1 reference

4 May 2018

http://europepmc.org/abstract/MED/29643418

published in

Nature Reviews Molecular Cell Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29643418 AND SRC:MED&resulttype=core&format=json

10 June 2020

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29643418 AND SRC:MED&resulttype=core&format=json

10 June 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29643418 AND SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

419-435

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29643418 AND SRC:MED&resulttype=core&format=json

How cells read TGF-beta signals

10 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

AMH and AMH receptor defects in persistent Müllerian duct syndrome

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

The genetic basis of aortic aneurysm

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Genetics of mammalian reproduction: modeling the end of the germline

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGF-β: the master regulator of fibrosis

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

BMP signalling in skeletal development, disease and repair.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

The changing role of TGFβ in healthy, ageing and osteoarthritic joints

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

BMP signaling in vascular diseases

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

https://api.crossref.org/works/10.1038/S41580-018-0007-0

1 reference

7 January 2021

The roles of TGFβ in the tumour microenvironment

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Targeting the Microenvironment in Advanced Colorectal Cancer

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Beyond TGFβ: roles of other TGFβ superfamily members in cancer

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGFβ signalling in context

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGF-β Family Signaling in Embryonic and Somatic Stem-Cell Renewal and Differentiation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

The harmonies played by TGF-β in stem cell biology

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Activin/Nodal signalling in stem cells.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Immunoregulation by members of the TGFβ superfamily

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Regulation of the Immune Response by TGF-β: From Conception to Autoimmunity and Infection

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGF beta signals through a heteromeric protein kinase receptor complex

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Mechanism of activation of the TGF-beta receptor

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Structural Biology and Evolution of the TGF-β Family

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Structural determinants of Smad function in TGF-β signaling.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

The DAN family: modulators of TGF-β signaling and beyond

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGF-β Signaling from Receptors to Smads

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Emergence of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin axis in transforming growth factor-β-induced epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Signaling Receptors for TGF-β Family Members

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Master transcription factors determine cell-type-specific responses to TGF-β signaling

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Nanog co-regulated by Nodal/Smad2 and Oct4 is required for pluripotency in developing mouse epiblast.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGF-β Tumor Suppression through a Lethal EMT.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Maternal Gdf3 is an obligatory cofactor in Nodal signaling for embryonic axis formation in zebrafish.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Gdf3 is required for robust Nodal signaling during germ layer formation and left-right patterning

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

BMP signalling: agony and antagony in the family

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Bone Morphogenetic Protein (BMP) signaling in development and human diseases

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

The transforming growth factor-beta system, a complex pattern of cross-reactive ligands and receptors

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Pituitary FSH is released by a heterodimer of the beta-subunits from the two forms of inhibin.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Dependence of Drosophila wing imaginal disc cytonemes on Decapentaplegic

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Kinetics of morphogen gradient formation.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Interaction of TGFβ and BMP Signaling Pathways during Chondrogenesis

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

GDF-5 can act as a context-dependent BMP-2 antagonist

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Induction of primordial germ cells from murine epiblasts by synergistic action of BMP4 and BMP8B signaling pathways

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Combinatorial Signal Perception in the BMP Pathway

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

A Poised Chromatin Platform for TGF-β Access to Master Regulators

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Physical and functional interaction of SMADs and p300/CBP

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

A Smad transcriptional corepressor

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

A Smad action turnover switch operated by WW domain readers of a phosphoserine code

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Cyclin-dependent kinases regulate the antiproliferative function of Smads

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Smad9 is a new type of transcriptional regulator in bone morphogenetic protein signaling

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Roles of activin family in pancreatic development and homeostasis

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Phosphatases in SMAD regulation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Force interacts with macromolecular structure in activation of TGF-β

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Regulation of TGF-β signal transduction by mono- and deubiquitylation of Smads

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

The emerging roles of deubiquitylating enzymes (DUBs) in the TGFβ and BMP pathways

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Ski and SnoN: negative regulators of TGF-beta signaling

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Regulation of TGF-β Family Signaling by Inhibitory Smads.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Bone morphogenetic proteins as regulators of iron metabolism

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

RGMs: Structural Insights, Molecular Regulation, and Downstream Signaling

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Blocking extracellular activation of myostatin as a strategy for treating muscle wasting

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Type beta transforming growth factor: a bifunctional regulator of cellular growth

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Two forms of transforming growth factor-β distinguished by multipotential haematopoietic progenitor cells

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Polypeptide transforming growth factors isolated from bovine sources and used for wound healing in vivo

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Human Smad3 and Smad4 are sequence-specific transcription activators

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF- effectors

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Characterization of a bone morphogenetic protein-responsive Smad-binding element

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

HEB associates with PRC2 and SMAD2/3 to regulate developmental fates

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Towards an understanding of cell-specific functions of signal-dependent transcription factors

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

A transcriptional partner for MAD proteins in TGF-beta signalling

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Smad4 and FAST-1 in the assembly of activin-responsive factor

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Signal integration in TGF-β, WNT, and Hippo pathways

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Signaling cross-talk between TGF-beta/BMP and other pathways

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Structural and functional characterization of the transforming growth factor-beta -induced Smad3/c-Jun transcriptional cooperativity.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

A self-enabling TGFbeta response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Super-enhancers in the control of cell identity and disease

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Master transcription factors and mediator establish super-enhancers at key cell identity genes

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Convergence of developmental and oncogenic signaling pathways at transcriptional super-enhancers

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

A genetic regulatory network for Xenopus mesendoderm formation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGF-β signaling to chromatin: how Smads regulate transcription during self-renewal and differentiation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Foxh1 Occupies cis-Regulatory Modules Prior to Dynamic Transcription Factor Interactions Controlling the Mesendoderm Gene Program.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Chromatin and transcriptional signatures for Nodal signaling during endoderm formation in hESCs

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

In Vivo Regulation of the Zebrafish Endoderm Progenitor Niche by T-Box Transcription Factors

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Distinct modes of SMAD2 chromatin binding and remodeling shape the transcriptional response to NODAL/Activin signaling.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

BMP signaling and its pSMAD1/5 target genes differentially regulate hair follicle stem cell lineages

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Dlx3 is a crucial regulator of hair follicle differentiation and cycling

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Brachyury and SMAD signalling collaboratively orchestrate distinct mesoderm and endoderm gene regulatory networks in differentiating human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Pluripotency factors regulate definitive endoderm specification through eomesodermin

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Signaling pathways in intestinal development and cancer

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Molecular mechanisms of Spemann's organizer formation: conserved growth factor synergy between Xenopus and mouse

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Transcriptional integration of Wnt and Nodal pathways in establishment of the Spemann organizer

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Maintenance of pluripotency in mouse ES cells without Trp53.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

P53 activity is essential for normal development in Xenopus

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Switch enhancers interpret TGF-β and Hippo signaling to control cell fate in human embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

SMADs and YAP compete to control elongation of β-catenin:LEF-1-recruited RNAPII during hESC differentiation.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Genomewide comprehensive analysis reveals critical cooperation between Smad and c-Fos in RANKL-induced osteoclastogenesis

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

https://api.crossref.org/works/10.1038/S41580-018-0007-0

1 reference

7 January 2021

TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Mechanisms of TGFβ-Induced Epithelial-Mesenchymal Transition

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGFbeta2 and TGFbeta3 have separate and sequential activities during epithelial-mesenchymal cell transformation in the embryonic heart.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Slug is an essential target of TGFbeta2 signaling in the developing chicken heart.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGF-β promotes heterogeneity and drug resistance in squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Epithelial-Mesenchymal Plasticity: A Central Regulator of Cancer Progression

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Metastasis is driven by sequential elevation of H-ras and Smad2 levels.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Role of Ras signaling in the induction of snail by transforming growth factor-beta.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Selection of self-reactive T cells in the thymus

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Transforming growth factor beta and cyclosporin A inhibit the inducible activity of the interleukin-2 gene in T cells through a noncanonical octamer-binding site

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Regulatory T cells: mechanisms of differentiation and function

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Control of regulatory T cell development by the transcription factor Foxp3

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Conversion of peripheral CD4 CD25- naive T cells to CD4 CD25 regulatory T cells by TGF-beta induction of transcription factor Foxp3

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

The transcription factor musculin promotes the unidirectional development of peripheral Treg cells by suppressing the TH2 transcriptional program

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Transforming growth factor-beta signaling curbs thymic negative selection promoting regulatory T cell development

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17 T helper cells

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Smad2 and Smad3 are redundantly essential for the TGF-beta-mediated regulation of regulatory T plasticity and Th1 development.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Smad2 positively regulates the generation of Th17 cells.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-β and suppresses T(H)2 differentiation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

A structural basis for mutational inactivation of the tumour suppressor Smad4

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Vertebrate endoderm development and organ formation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Activation of Akt signaling in prostate induces a TGFβ-mediated restraint on cancer progression and metastasis

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Krüppel-like factor 5 is essential for proliferation and survival of mouse intestinal epithelial stem cells

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Dissection of transcriptional and cis-regulatory control of differentiation in human pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

KLF5 activates microRNA 200 transcription to maintain epithelial characteristics and prevent induced epithelial-mesenchymal transition in epithelial cells

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Pancreatic Adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Enhanced expression of the type II transforming growth factor-beta receptor is associated with decreased survival in human pancreatic cancer

2 references

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

12 December 2020

Epithelial-mesenchymal transition (EMT) and metastasis: yes, no, maybe?

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Transforming growth factor-beta stimulates parathyroid hormone-related protein and osteolytic metastases via Smad and mitogen-activated protein kinase signaling pathways

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Metastatic colonization by circulating tumour cells

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0007-0

7 January 2021

BMP-2 and OP-1 exert direct and opposite effects on renal branching morphogenesis

1 reference

12 December 2020

Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif

1 reference

12 December 2020

Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-beta1 and Ha-Ras: steps towards invasiveness.

1 reference

12 December 2020

Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways.

1 reference

12 December 2020

PARP-1 attenuates Smad-mediated transcription

1 reference

12 December 2020

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

1 reference

12 December 2020

Blockade of only TGF-β 1 and 2 is sufficient to enhance the efficacy of vaccine and PD-1 checkpoint blockade immunotherapy.

1 reference

12 December 2020

10.1038/S41580-018-0007-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29643418 AND SRC:MED&resulttype=core&format=json

10 June 2020

1 reference