Metabolic engineering of Pichia pastoris. (Q52431940)

1 May 2018

http://europepmc.org/abstract/MED/29704654

title

Metabolic engineering of Pichia pastoris. (English)

1 reference

1 May 2018

http://europepmc.org/abstract/MED/29704654

main subject

Pichia pastoris

object named as

Pichia pastoris

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29704654 AND SRC:MED&resulttype=core&format=json

11 June 2020

Matthias Steiger

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29704654 AND SRC:MED&resulttype=core&format=json

11 June 2020

Diethard Mattanovich

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29704654 AND SRC:MED&resulttype=core&format=json

11 June 2020

author name string

David A Peña

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29704654 AND SRC:MED&resulttype=core&format=json

11 June 2020

Jürgen Zanghellini

3

1 reference

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11 June 2020

publication date

25 April 2018

1 reference

1 May 2018

http://europepmc.org/abstract/MED/29704654

published in

Metabolic Engineering

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29704654 AND SRC:MED&resulttype=core&format=json

11 June 2020

volume

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29704654 AND SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

2-15

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29704654 AND SRC:MED&resulttype=core&format=json

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11 June 2020

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Synthesis of polyhydroxyalkanoate in the peroxisome of Pichia pastoris

7 January 2021

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Induction without methanol: novel regulated promoters enable high-level expression in Pichia pastoris.

7 January 2021

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GoldenPiCS: a Golden Gate-derived modular cloning system for applied synthetic biology in the yeast Pichia pastoris

7 January 2021

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Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

7 January 2021

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Implementing CRISPR-Cas technologies in conventional and non-conventional yeasts: Current state and future prospects

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In Pichia pastoris, growth rate regulates protein synthesis and secretion, mating and stress response.

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Pichia pastoris Exhibits High Viability and a Low Maintenance Energy Requirement at Near-Zero Specific Growth Rates.

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Systems-level organization of yeast methylotrophic lifestyle.

7 January 2021

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Metabolomics sampling of Pichia pastoris revisited: rapid filtration prevents metabolite loss during quenching.

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Dynamic genome-scale metabolic modeling of the yeast Pichia pastoris

7 January 2021

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Construction of robust dynamic genome-scale metabolic model structures of Saccharomyces cerevisiae through iterative re-parameterization

7 January 2021

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Improving the phenotype predictions of a yeast genome-scale metabolic model by incorporating enzymatic constraints

7 January 2021

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An efficient tool for metabolic pathway construction and gene integration for Aspergillus niger.

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Metabolic networks in motion: 13C-based flux analysis

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A high-throughput expression screening platform to optimize the production of antimicrobial peptides

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DNA assembler, an in vivo genetic method for rapid construction of biochemical pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

A new type of gene-disruption cassette with a rescue gene for Pichia pastoris

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Enhanced hydrolysis of lignocellulosic biomass: Bi-functional enzyme complexes expressed in Pichia pastoris improve bioethanol production from Miscanthus sinensis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Exploring the potential of genome editing CRISPR-Cas9 technology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Metabolic engineering of Pichia pastoris for production of isobutanol and isobutyl acetate.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Genome-scale metabolic model of methylotrophic yeast Pichia pastoris and its use for in silico analysis of heterologous protein production.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Amino acid biosynthesis and metabolic flux profiling of Pichia pastoris

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Metabolic flux profiling of Pichia pastoris grown on glycerol/methanol mixtures in chemostat cultures at low and high dilution rates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Invertase gene (SUC2) of Saccharomyces cerevisiae as a dominant marker for transformation of Pichia pastoris.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Refined Pichia pastoris reference genome sequence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Genetic mapping of quantitative phenotypic traits in Saccharomyces cerevisiae

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Integrating metabolic modeling and population heterogeneity analysis into optimizing recombinant protein production by Komagataella (Pichia) pastoris.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Integration and Validation of the Genome-Scale Metabolic Models of Pichia pastoris: A Comprehensive Update of Protein Glycosylation Pathways, Lipid and Energy Metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Fine-tuning the P. pastoris iMT1026 genome-scale metabolic model for improved prediction of growth on methanol or glycerol as sole carbon sources

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

The development of metabolomic sampling procedures for Pichia pastoris, and baseline metabolome data.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Rapid screening of cellular stress responses in recombinant Pichia pastoris strains using metabolite profiling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Improved Gene Targeting through Cell Cycle Synchronization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Curation of the genome annotation of Pichia pastoris (Komagataella phaffii) CBS7435 from gene level to protein function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

The significance of peroxisomes in methanol metabolism in methylotrophic yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Current state and challenges for dynamic metabolic modeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Metabolic flux screening of Saccharomyces cerevisiae single knockout strains on glucose and galactose supports elucidation of gene function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

In vivo synthesis of mammalian-like, hybrid-type N-glycans in Pichia pastoris

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Regulation of Pichia pastoris promoters and its consequences for protein production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Synthetic core promoters for Pichia pastoris

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Restriction site free cloning (RSFC) plasmid family for seamless, sequence independent cloning in Pichia pastoris

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

A Toolbox of Diverse Promoters Related to Methanol Utilization: Functionally Verified Parts for Heterologous Pathway Expression in Pichia pastoris

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Effect of plasmid design and type of integration event on recombinant protein expression in Pichia pastoris

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Methanol independent induction in Pichia pastoris by simple derepressed overexpression of single transcription factors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Maintenance-energy requirements and robustness of Saccharomyces cerevisiae at aerobic near-zero specific growth rates.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Synthetic biology and molecular genetics in non-conventional yeasts: Current tools and future advances

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Methanol-Independent Protein Expression by AOX1 Promoter with trans-Acting Elements Engineering and Glucose-Glycerol-Shift Induction in Pichia pastoris.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Methylotrophic yeasts--1986.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Characterization of Terminators in Saccharomyces cerevisiae and an Exploration of Factors Affecting Their Strength

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

A toolbox of endogenous and heterologous nuclear localization sequences for the methylotrophic yeast Pichia pastoris.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Combinatorial optimization of CRISPR/Cas9 expression enables precision genome engineering in the methylotrophic yeast Pichia pastoris

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Expanding the CRISPR/Cas9 toolkit for Pichia pastoris with efficient donor integration and alternative resistance markers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Current progress in computational metabolomics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Production of the sesquiterpenoid ( )-nootkatone by metabolic engineering of Pichia pastoris

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Metabolic Burden: Cornerstones in Synthetic Biology and Metabolic Engineering Applications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

High efficiency transformation by electroporation of Pichia pastoris pretreated with lithium acetate and dithiothreitol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Methylotrophic yeast Pichia pastoris as a chassis organism for polyketide synthesis via the full citrinin biosynthetic pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

The phylogenetic relationships of methanol-assimilating yeasts based on the partial sequences of 18S and 26S ribosomal RNAs: the proposal of Komagataella gen. nov. (Saccharomycetaceae).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

A genome-wide activity assessment of terminator regions in Saccharomyces cerevisiae provides a ″terminatome″ toolbox

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Controlling AOX1 promoter strength in Pichia pastoris by manipulating poly (dA:dT) tracts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Engineering strategies for enhanced production of protein and bio-products in Pichia pastoris: A review

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Optimization of a glycoengineered Pichia pastoris cultivation process for commercial antibody production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Comprehensive reconstruction and evaluation of Pichia pastoris genome-scale metabolic model that accounts for 1243 ORFs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Systems biotechnology for protein production in Pichia pastoris.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

(13)C-based metabolic flux analysis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

13 C metabolic flux profiling of Pichia pastoris grown in aerobic batch cultures on glucose revealed high relative anabolic use of TCA cycle and limited incorporation of provided precursors of branched-chain amino acids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

Enhancing Biosynthesis of a Ginsenoside Precursor by Self-Assembly of Two Key Enzymes in Pichia pastoris

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMBEN.2018.04.017

10.1016/J.YMBEN.2018.04.017

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29704654 AND SRC:MED&resulttype=core&format=json

11 June 2020

1 reference