Transgenic mice expressing the intracellular domain of the p75 neurotrophin receptor undergo neuronal apoptosis. (Q52192838)

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5 November 2019

title

Transgenic mice expressing the intracellular domain of the p75 neurotrophin receptor undergo neuronal apoptosis (English)

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M Majdan

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C Lachance

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A Gloster

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R Aloyz

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C Zeindler

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S Bamji

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A Bhakar

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D Belliveau

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J Fawcett

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F D Miller

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P A Barker

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language of work or name

English

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publication date

1 September 1997

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5 November 2019

published in

Journal of Neuroscience

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volume

17

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issue

18

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page(s)

6988-6998

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Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells

5 November 2019

cites work

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Methods for determining numbers of cells and synapses: a case for more uniform standards of review

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Survival of cholinergic forebrain neurons in developing p75NGFR-deficient mice

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TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

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Response of facial and rubrospinal neurons to axotomy: changes in mRNA expression for cytoskeletal proteins and GAP-43.

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Methods for analyzing c-Jun kinase

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Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons

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Dorsal root ganglion neurons expressing trk are selectively sensitive to NGF deprivation in utero

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NGF and neurotrophin-3 both activate TrkA on sympathetic neurons but differentially regulate survival and neuritogenesis

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A region of the 75 kDa neurotrophin receptor homologous to the death domains of TNFR‐I and Fas

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12 December 2020

A consideration of neural counting methods

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12 December 2020

The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development

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12 December 2020

Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation

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12 December 2020

Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95

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Role of neurotrophins in mouse neuronal development

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Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor

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p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins

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Protein-tyrosine phosphatase inhibitors block tumor necrosis factor-dependent activation of the nuclear transcription factor NF-kappa B.

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Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75.

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FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

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High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

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Transcriptional repression of the growth-associated T alpha1 alpha-tubulin gene by target contact.

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Emerging families of cytokines and receptors

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Transducers of life and death: TNF receptor superfamily and associated proteins

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Self-association of the Death Domains of the p55 Tumor Necrosis Factor (TNF) Receptor and Fas/APO1 Prompts Signaling for TNF and Fas/APO1 Effects

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12 December 2020

The T alpha 1 alpha-tubulin promoter specifies gene expression as a function of neuronal growth and regeneration in transgenic mice

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12 December 2020

A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

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12 December 2020

Positive and negative effects of neurotrophins on the isthmo-optic nucleus in chick embryos

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12 December 2020

Gene transfer and molecular cloning of the rat nerve growth factor receptor

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12 December 2020

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

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12 December 2020

Early events in neurotrophin signalling via Trk and p75 receptors

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12 December 2020

Comparison of the expression of a T alpha 1:nlacZ transgene and T alpha 1 alpha-tubulin mRNA in the mature central nervous system

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12 December 2020

Nerve growth factor receptor immunoreactivity is transiently associated with the subplate neurons of the mammalian cerebral cortex

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12 December 2020

Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells

1 reference

12 December 2020

p75LNGFR regulates Trk signal transduction and NGF-induced neuronal differentiation in MAH cells

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12 December 2020

A novel domain within the 55 kd TNF receptor signals cell death

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12 December 2020

Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation

1 reference

12 December 2020

Apoptosis by death factor

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12 December 2020

Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75.

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12 December 2020

Neurotrophins induce sphingomyelin hydrolysis. Modulation by co-expression of p75NTR with Trk receptors

1 reference

12 December 2020

Induction of cell death by endogenous nerve growth factor through its p75 receptor

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12 December 2020

The low affinity neurotrophin receptor, p75LNTR, is palmitoylated by thioester formation through cysteine 279.

1 reference

12 December 2020

10.1523/JNEUROSCI.17-18-06988.1997

Identifiers

DOI

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5 November 2019

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5 November 2019

PubMed publication ID

9278534

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