Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulin (Q51819137)

13 April 2018

title

Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulin (English)

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13 April 2018

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Katharine A Young

1

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13 April 2018

John H Caldwell

series ordinal

2

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13 April 2018

language of work or name

English

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publication date

3 March 2005

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13 April 2018

number of pages

22

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inferred from page(s)

published in

Journal of Physiology

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13 April 2018

volume

565

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13 April 2018

issue

Pt 2

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13 April 2018

page(s)

349-370

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13 April 2018

Channel cytoplasmic loops alter voltage-dependent sodium channel activation in an isoform-specific manner

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Solution structure of Ca(2 )-calmodulin reveals flexible hand-like properties of its domains

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Ion channel properties underlying axonal action potential initiation in pyramidal neurons

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Isoform-specific modulation of voltage-gated Na( ) channels by calmodulin.

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Implication of the C-terminal region of the alpha-subunit of voltage-gated sodium channels in fast inactivation

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C terminus L-type Ca2 channel calmodulin-binding domains are 'auto-agonist' ligands in rabbit ventricular myocytes

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Preassociation of calmodulin with voltage-gated Ca(2 ) channels revealed by FRET in single living cells

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FRET two-hybrid mapping reveals function and location of L-type Ca2 channel CaM preassociation.

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Calcium-induced structural changes and domain autonomy in calmodulin

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Mechanisms of sodium channel inactivation

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Paroxysms of excitement: sodium channel dysfunction in heart and brain

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Calmodulin mediates Ca2 sensitivity of sodium channels

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Solution structure of calcium-free calmodulin

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It is calmodulin after all! Mediator of the calcium modulation of multiple ion channels

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Unified mechanisms of Ca2 regulation across the Ca2 channel family

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Role of the C-terminal domain in inactivation of brain and cardiac sodium channels

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Functional modulation of human brain Nav1.3 sodium channels, expressed in mammalian cells, by auxiliary beta 1, beta 2 and beta 3 subunits

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Functional stoichiometry and local enrichment of calmodulin interacting with Ca2 channels

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Regulatory interaction of sodium channel IQ-motif with calmodulin C-terminal lobe

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Interlobe communication in multiple calcium-binding site mutants of Drosophila calmodulin

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Calmodulin is a limiting factor in the cell

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A New Role for IQ Motif Proteins in Regulating Calmodulin Function

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Ca2 -induced inhibition of the cardiac Ca2 channel depends on calmodulin

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Calmodulin as an ion channel subunit

21 January 2018

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Structure of the gating domain of a Ca2 -activated K channel complexed with Ca2 /calmodulin

21 January 2018

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The newly synthesized selective Ca2 /calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h cells

21 January 2018

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A calcium sensor in the sodium channel modulates cardiac excitability

21 January 2018

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Two distinct myosin light chain structures are induced by specific variations within the bound IQ motifs-functional implications

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Functional differences in Kv1.5 currents expressed in mammalian cell lines are due to the presence of endogenous Kv beta 2.1 subunits

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Phosphorylation of the rat skeletal muscle sodium channel by cyclic AMP-dependent protein kinase

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Calcium-induced conformational transition revealed by the solution structure of apo calmodulin

21 January 2018

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Calmodulin supports both inactivation and facilitation of L-type calcium channels.

21 January 2018

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Ca2 -sensitive inactivation of L-type Ca2 channels depends on multiple cytoplasmic amino acid sequences of the alpha1C subunit

21 January 2018

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Calmodulin binds to the C terminus of sodium channels Nav1.4 and Nav1.6 and differentially modulates their functional properties.

21 January 2018

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12 December 2020

Site-directed mutation of the trigger calcium-binding sites in cardiac troponin C.

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12 December 2020

Protein kinase A phosphorylation enhances sodium channel currents in Xenopus oocytes

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12 December 2020

Domains responsible for constitutive and Ca(2 )-dependent interactions between calmodulin and small conductance Ca(2 )-activated potassium channels.

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12 December 2020

Novel interaction of the voltage-dependent sodium channel (VDSC) with calmodulin: does VDSC acquire calmodulin-mediated Ca2 -sensitivity?

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12 December 2020

I. Cellular and molecular biology of sodium channel beta-subunits: therapeutic implications for pain?

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12 December 2020

Very negative potential for half-inactivation of, and effects of anions on, voltage-dependent sodium currents in acutely isolated rat olfactory receptor neurons

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12 December 2020

Na( ) channel regulation by calmodulin kinase II in rat cerebellar granule cells

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12 December 2020

Rotational Dynamics of Calcium-Free Calmodulin Studied by 15N-NMR Relaxation Measurements

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12 December 2020

Sequence motifs for calmodulin recognition

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12 December 2020

Calmodulin is the Ca2 sensor for Ca2 -dependent inactivation of L-type calcium channels

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12 December 2020

10.1113/JPHYSIOL.2004.081422

Identifiers

DOI

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13 April 2018

PMC publication ID

1464525

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13 April 2018