Multivalent interactions with gp120 are required for the anti-HIV activity of Cyanovirin. (Q51805853)

PubMed publication ID

19235857

12 April 2018

http://europepmc.org/abstract/MED/19235857

title

Multivalent interactions with gp120 are required for the anti-HIV activity of Cyanovirin (English)

1 reference

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13 May 2020

author name string

Yinan Liu

1

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13 May 2020

Jacob R Carroll

2

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13 May 2020

Lindsey A Holt

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6961781&resulttype=core&format=json

13 May 2020

James McMahon

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6961781&resulttype=core&format=json

13 May 2020

Barbara Giomarelli

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6961781&resulttype=core&format=json

13 May 2020

Giovanna Ghirlanda

6

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13 May 2020

publication date

1 January 2009

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PubMed publication ID

19235857

12 April 2018

http://europepmc.org/abstract/MED/19235857

published in

Biopolymers

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13 May 2020

volume

92

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13 May 2020

issue

3

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13 May 2020

page(s)

194-200

1 reference

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The highly specific carbohydrate-binding protein cyanovirin-N: structure, anti-HIV/Ebola activity and possibilities for therapy

13 May 2020

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1002/BIP.21173

Carbohydrate-binding agents: a potential future cornerstone for the chemotherapy of enveloped viruses?

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002/BIP.21173

Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120.

21 January 2018

1 reference

12 December 2020

Inhibition of HIV entry by carbohydrate-binding proteins

1 reference

12 December 2020

Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy

1 reference

12 December 2020

Domain-swapped structure of a mutant of cyanovirin-N

1 reference

12 December 2020

Structural studies of algal lectins with anti-HIV activity.

1 reference

12 December 2020

A semiautomated multiparameter approach for anti-HIV drug screening

1 reference

12 December 2020

Actinohivin, a novel anti-human immunodeficiency virus protein from an actinomycete, inhibits viral entry to cells by binding high-mannose type sugar chains of gp120.

1 reference

12 December 2020

Multivalent protein-carbohydrate interactions. A new paradigm for supermolecular assembly and signal transduction

1 reference

12 December 2020

Crystal structures of the HIV-1 inhibitory cyanobacterial protein MVL free and bound to Man3GlcNAc2: structural basis for specificity and high-affinity binding to the core pentasaccharide from n-linked oligomannoside

1 reference

12 December 2020

Printed covalent glycan array for ligand profiling of diverse glycan binding proteins

1 reference

12 December 2020

Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development

1 reference

12 December 2020

Engineering an obligate domain-swapped dimer of cyanovirin-N with enhanced anti-HIV activity.

1 reference

12 December 2020

Flipping the switch from monomeric to dimeric CV-N has little effect on antiviral activity

1 reference

12 December 2020

Conformational gating of dimannose binding to the antiviral protein cyanovirin revealed from the crystal structure at 1.35 Å resolution

1 reference

12 December 2020

Functional homologs of cyanovirin-N amenable to mass production in prokaryotic and eukaryotic hosts

1 reference

12 December 2020

Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp

1 reference

12 December 2020

Dissecting carbohydrate–Cyanovirin-N binding by structure-guided mutagenesis: functional implications for viral entry inhibition

1 reference

12 December 2020

Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific manner

1 reference

12 December 2020

A monovalent mutant of cyanovirin-N provides insight into the role of multiple interactions with gp120 for antiviral activity

1 reference

12 December 2020

Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding.

1 reference

12 December 2020

Potent inhibition of HIV-1 fusion by cyanovirin-N requires only a single high affinity carbohydrate binding site: characterization of low affinity carbohydrate binding site knockout mutants

1 reference

12 December 2020

Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides

1 reference

12 December 2020

Solution structure of cyanovirin-N, a potent HIV-inactivating protein

1 reference

12 December 2020

Fusogenic mechanisms of enveloped-virus glycoproteins analyzed by a novel recombinant vaccinia virus-based assay quantitating cell fusion-dependent reporter gene activation.

1 reference

12 December 2020

High-throughput carbohydrate microarray analysis of 24 lectins

1 reference

12 December 2020

Actinohivin, a novel anti-HIV protein from an actinomycete that inhibits syncytium formation: isolation, characterization, and biological activities

1 reference

12 December 2020

Cyanovirin-N, a potent human immunodeficiency virus-inactivating protein, blocks both CD4-dependent and CD4-independent binding of soluble gp120 (sgp120) to target cells, inhibits sCD4-induced binding of sgp120 to cell-associated CXCR4, and dissocia

1 reference

12 December 2020

Discovery of a stable dimeric mutant of cyanovirin-N (CV-N) from a T7 phage-displayed CV-N mutant library

1 reference

12 December 2020

The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures

1 reference

12 December 2020

Solution structure of a cyanovirin-N:Man alpha 1-2Man alpha complex: structural basis for high-affinity carbohydrate-mediated binding to gp120

1 reference

12 December 2020

Exploiting the defensive sugars of HIV-1 for drug and vaccine design

1 reference

12 December 2020

Design and initial characterization of a circular permuted variant of the potent HIV-inactivating protein cyanovirin-N.

1 reference

12 December 2020

Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models

1 reference

12 December 2020

Crystal structure of cyanovirin-N, a potent HIV-inactivating protein, shows unexpected domain swapping

1 reference

12 December 2020

Identifiers

DOI

10.1002/BIP.21173

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6961781&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6961781&resulttype=core&format=json

13 May 2020

PubMed publication ID

19235857

1 reference