MDM2 is overexpressed and regulated by the eukaryotic translation initiation factor 4E (eIF4E) in human squamous cell carcinoma of esophagus (Q51743355)

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scientific article published on 13 November 2010

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English	MDM2 is overexpressed and regulated by the eukaryotic translation initiation factor 4E (eIF4E) in human squamous cell carcinoma of esophagus	scientific article published on 13 November 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21080085

MDM2 is overexpressed and regulated by the eukaryotic translation initiation factor 4E (eIF4E) in human squamous cell carcinoma of esophagus (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21080085

1 reference

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Han-Shui Hsu

1

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21080085

Hsin-Wu Chen

2

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21080085

Chia-Li Kao

3

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21080085

Min-Li Wu

4

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21080085

Anna Fen-Yau Li

5

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21080085

Tzu-Hao Cheng

6

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21080085

publication date

13 November 2010

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Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21080085

Annals of Surgical Oncology

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Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21080085

18

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21080085

5

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21080085

1469-1477

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21080085

Controlling gene expression through RNA regulons: the role of the eukaryotic translation initiation factor eIF4E.

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

eIF-4E expression and its role in malignancies and metastases.

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

eIF4E expression in tumors: its possible role in progression of malignancies

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Eukaryotic initiation factor 4E

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Dissecting eIF4E action in tumorigenesis

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Control of translation initiation in animals.

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

eIF4E, the mRNA cap-binding protein: from basic discovery to translational research

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Gene-specific regulation by general translation factors

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential Recruitment of Existing mRNAs to Polysomes

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

A new twist in the feedback loop: stress-activated MDM2 destabilization is required for p53 activation

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

MDM2 gene amplification and expression in non-small-cell lung cancer: immunohistochemical expression of its protein is a favourable prognostic marker in patients without p53 protein accumulation

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Aberrant expression of pRb, p16, p14ARF, MDM2, p21 and p53 in squamous cell carcinomas of lung.

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Correlation of p53, MDM2 and p14(ARF) protein expression in human esophageal squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Overexpression of MDM2, due to enhanced translation, results in inactivation of wild-type p53 in Burkitt's lymphoma cells.

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Rapamycin increases the p53/MDM2 protein ratio and p53-dependent apoptosis by translational inhibition of mdm2 in cancer cells

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

A novel role for IGF-1R in p53-mediated apoptosis through translational modulation of the p53-Mdm2 feedback loop

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Hypophosphorylated ASF/SF2 binds TAP and is present in messenger ribonucleoproteins

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

eIF4E is a central node of an RNA regulon that governs cellular proliferation

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3'UTR

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Met acts on Mdm2 via mTOR to signal cell survival during development.

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Targeting Mdm2 and Mdmx in cancer therapy: better living through medicinal chemistry?

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

The MDM2 gene amplification database

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Correlation of p53 mutations with epidermal growth factor receptor overexpression and absence of mdm2 amplification in human esophageal carcinomas.

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Gene amplification profiling of esophageal squamous cell carcinomas by DNA array CGH.

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Expression of Akt and Mdm2 in human esophageal squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

The two upstream open reading frames of oncogene mdm2 have different translational regulatory properties

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Prospective study of eukaryotic initiation factor 4E protein elevation and breast cancer outcome

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Expression of eukaryotic initiation factor 4E in gastric adenocarcinoma and its association with clinical outcome.

1 reference

https://api.crossref.org/works/10.1245/S10434-010-1428-Y

21 January 2018

Identifiers

10.1245/S10434-010-1428-Y

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21080085

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 April 2018

http://europepmc.org/abstract/MED/21080085

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