L503F variant of carnitine/organic cation transporter 1 efficiently transports metformin and other biguanides. (Q51677782)

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16 March 2020

title

L503F variant of carnitine/organic cation transporter 1 efficiently transports metformin and other biguanides (English)

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16 March 2020

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4

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16 March 2020

author name string

Azusa Futatsugi

1

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16 March 2020

Yusuke Masuo

2

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16 March 2020

Shiori Kawabata

3

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Yukio Kato

5

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publication date

28 June 2016

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Journal of Pharmacy and Pharmacology

16 March 2020

published in

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volume

68

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issue

9

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page(s)

1160-1169

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Current understanding of metformin effect on the control of hyperglycemia in diabetes

16 March 2020

cites work

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Metformin-associated lactic acidosis: Current perspectives on causes and risk

21 January 2018

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Metformin and other antidiabetic agents in renal failure patients

21 January 2018

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Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics

21 January 2018

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Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin.

21 January 2018

1 reference

Identification and functional characterization of a new human kidney-specific H /organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.

21 January 2018

1 reference

Functional expression of carnitine/organic cation transporter OCTN1/SLC22A4 in mouse small intestine and liver

21 January 2018

1 reference

Involvement of OCTN1 (SLC22A4) in pH-dependent transport of organic cations.

21 January 2018

1 reference

Functional expression of carnitine/organic cation transporter OCTN1 in mouse brain neurons: possible involvement in neuronal differentiation.

21 January 2018

1 reference

Involvement of carnitine/organic cation transporter OCTN1/SLC22A4 in gastrointestinal absorption of metformin.

21 January 2018

1 reference

Role of organic cation/carnitine transporter 1 in uptake of phenformin and inhibitory effect on complex I respiration in mitochondria

21 January 2018

1 reference

Discovery of the ergothioneine transporter

21 January 2018

1 reference

Functional effects of protein sequence polymorphisms in the organic cation/ergothioneine transporter OCTN1 (SLC22A4).

21 January 2018

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The human OCTN1 (SLC22A4) reconstituted in liposomes catalyzes acetylcholine transport which is defective in the mutant L503F associated to the Crohn's disease.

21 January 2018

1 reference

Cloning and characterization of a novel human pH‐dependent organic cation transporter, OCTN1

21 January 2018

1 reference

Evidence of carrier-mediated transport in the penetration of donepezil into the rat brain

21 January 2018

1 reference

Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons.

21 January 2018

1 reference

Effects of genetic variation in the novel organic cation transporter, OCTN1, on the renal clearance of gabapentin

21 January 2018

1 reference

Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter

21 January 2018

1 reference

Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium

21 January 2018

1 reference

SLC18: Vesicular neurotransmitter transporters for monoamines and acetylcholine

21 January 2018

1 reference

Functional role of the 503F variant of the organic cation transporter OCTN1 in Crohn's disease

21 January 2018

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Functional variants of OCTN cation transporter genes are associated with Crohn disease

21 January 2018

1 reference

Functional analysis of novel variants in the organic cation/ergothioneine transporter 1 identified in Singapore populations

21 January 2018

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Circumventing the Crabtree Effect: Replacing Media Glucose with Galactose Increases Susceptibility of HepG2 Cells to Mitochondrial Toxicants

21 January 2018

1 reference

Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1.

21 January 2018

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Pharmacokinetic-pharmacodynamic analysis of the glucose-lowering effect of metformin in diabetic rats reveals first-pass pharmacodynamic effect

21 January 2018

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The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin.

21 January 2018

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Inhibition of hepatic gluconeogenesis by metformin. Synergism with insulin.

21 January 2018

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Novel localization of OCTN1, an organic cation/carnitine transporter, to mammalian mitochondria

21 January 2018

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Influences of organic cation transporter polymorphisms on the population pharmacokinetics of metformin in healthy subjects

21 January 2018

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Increased ergothioneine tissue concentrations in carriers of the Crohn's disease risk-associated 503F variant of the organic cation transporter OCTN1.

21 January 2018

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Dietary sources and antioxidant effects of ergothioneine

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/JPHP.12574

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16 March 2020

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