Prognostic significance of IKZF1 deletion in adult B cell acute lymphoblastic leukemia: a meta-analysis (Q51343198)

3 April 2018

meta-analysis

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title

Prognostic significance of IKZF1 deletion in adult B cell acute lymphoblastic leukemia: a meta-analysis (English)

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3 April 2018

main subject

lymphoblastic leukemia

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Wanhua Zhang

1

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3 April 2018

Pu Kuang

2

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3 April 2018

He Li

3

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3 April 2018

Fengjuan Wang

4

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3 April 2018

Yu Wang

5

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3 April 2018

publication date

4 November 2016

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3 April 2018

published in

Annals of Hematology

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3 April 2018

volume

96

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3 April 2018

issue

2

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3 April 2018

page(s)

215-225

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3 April 2018

New and emerging prognostic and predictive genetic biomarkers in B-cell precursor acute lymphoblastic leukemia

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High frequency of IKZF1 genetic alterations in adult patients with B-cell acute lymphoblastic leukemia

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Oncogenetics and minimal residual disease are independent outcome predictors in adult patients with acute lymphoblastic leukemia

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Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute

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IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report

21 January 2018

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IKZF1 deletion is an independent prognostic marker in childhood B-cell precursor acute lymphoblastic leukemia, and distinguishes patients benefiting from pulses during maintenance therapy: results of the EORTC Children's Leukemia Group study 58951.

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IKZF1 status as a prognostic feature in BCR-ABL1-positive childhood ALL.

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Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL.

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Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011.

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IKZF1 deletion is associated with a poor outcome in pediatric B-cell precursor acute lymphoblastic leukemia in Japan

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IKZF1 alterations and expression of CRLF2 predict prognosis in adult Chinese patients with B-cell precursor acute lymphoblastic leukemia

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Prognostic significance of copy number alterations in adolescent and adult patients with precursor B acute lymphoblastic leukemia enrolled in PETHEMA protocols.

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Impact of IKZF1 deletions on long-term outcomes of allo-SCT following imatinib-based chemotherapy in adult Philadelphia chromosome-positive ALL.

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21 January 2018

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ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia.

21 January 2018

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An intragenic ERG deletion is a marker of an oncogenic subtype of B-cell precursor acute lymphoblastic leukemia with a favorable outcome despite frequent IKZF1 deletions.

21 January 2018

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High CRLF2 expression associates with IKZF1 dysfunction in adult acute lymphoblastic leukemia without CRLF2 rearrangement

21 January 2018

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CRLF2 overexpression identifies an unfavourable subgroup of adult B-cell precursor acute lymphoblastic leukemia lacking recurrent genetic abnormalities

21 January 2018

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IKZF1 and CRLF2 gene alterations correlate with poor prognosis in Japanese BCR-ABL1-negative high-risk B-cell precursor acute lymphoblastic leukemia.

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Impact of complete molecular response on survival in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

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Minimal residual disease assessed by multi-parameter flow cytometry is highly prognostic in adult patients with acute lymphoblastic leukaemia

21 January 2018

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Early MRD response as a prognostic factor in adult patients with acute lymphoblastic leukemia

21 January 2018

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Tumor suppressor IKZF1 mediates glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.

21 January 2018

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Ikaros deletions in BCR-ABL-negative childhood acute lymphoblastic leukemia are associated with a distinct gene expression signature but do not result in intrinsic chemoresistance

21 January 2018

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Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia

21 January 2018

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Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia.

21 January 2018

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BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

21 January 2018

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10.1007/S00277-016-2869-6

21 January 2018

Identifiers

DOI

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3 April 2018

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3 April 2018