ErbB2 blockade with Herceptin (trastuzumab) enhances peripheral nerve regeneration after repair of acute or chronic peripheral nerve injury (Q51339711)

3 April 2018

title

ErbB2 blockade with Herceptin (trastuzumab) enhances peripheral nerve regeneration after repair of acute or chronic peripheral nerve injury (English)

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3 April 2018

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J Michael Hendry

1

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3 April 2018

M Cecilia Alvarez-Veronesi

2

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3 April 2018

Eva Placheta

3

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Jennifer J Zhang

4

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Tessa Gordon

5

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Gregory H Borschel

6

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publication date

9 May 2016

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3 April 2018

published in

Annals of Neurology

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3 April 2018

volume

80

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issue

1

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page(s)

112-126

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A decline in glial cell-line-derived neurotrophic factor expression is associated with impaired regeneration after long-term Schwann cell denervation.

cites work

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Schwann cells express motor and sensory phenotypes that regulate axon regeneration.

21 January 2018

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Glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor sustain the axonal regeneration of chronically axotomized motoneurons in vivo

21 January 2018

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Schwann cell phenotype is regulated by axon modality and central-peripheral location, and persists in vitro

21 January 2018

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GDNF released from microspheres enhances nerve regeneration after delayed repair

21 January 2018

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Rescue and sprouting of motoneurons following ventral root avulsion and reimplantation combined with intraspinal adeno-associated viral vector-mediated expression of glial cell line-derived neurotrophic factor or brain-derived neurotrophic factor.

21 January 2018

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The role of neurotrophic factors in nerve regeneration

21 January 2018

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A dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor

21 January 2018

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Nerve cross-bridging to enhance nerve regeneration in a rat model of delayed nerve repair

21 January 2018

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Side-To-Side Nerve Bridges Support Donor Axon Regeneration Into Chronically Denervated Nerves and Are Associated With Characteristic Changes in Schwann Cell Phenotype

21 January 2018

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Axon-induced mitogenesis of human Schwann cells involves heregulin and p185erbB2.

21 January 2018

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Axonal neuregulin-1 regulates myelin sheath thickness

21 January 2018

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Axonally derived neuregulin-1 is required for remyelination and regeneration after nerve injury in adulthood.

21 January 2018

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Humanization of an anti-p185HER2 antibody for human cancer therapy

21 January 2018

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The ErbB2 inhibitor Herceptin (Trastuzumab) promotes axonal outgrowth four weeks after acute nerve transection and repair

21 January 2018

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ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury.

21 January 2018

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A new model for facial nerve research: the novel transgenic Thy1-GFP rat.

21 January 2018

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Application and potential limitations of animal models utilized in the development of trastuzumab (Herceptin): a case study

21 January 2018

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Neural stem cells as a novel platform for tumor-specific delivery of therapeutic antibodies

21 January 2018

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Transforming growth factor-beta and forskolin attenuate the adverse effects of long-term Schwann cell denervation on peripheral nerve regeneration in vivo

21 January 2018

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Schwann cell proliferation in developing mouse sciatic nerve. A radioautographic study

21 January 2018

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EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans

21 January 2018

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ErbB1 epidermal growth factor receptor is a valid target for reducing the effects of multiple inhibitors of axonal regeneration.

21 January 2018

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The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors

21 January 2018

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Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha

21 January 2018

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The ErbB signaling network: receptor heterodimerization in development and cancer

21 January 2018

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Untangling the ErbB signalling network

21 January 2018

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The deaf and the dumb: the biology of ErbB-2 and ErbB-3

21 January 2018

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Mechanics of EGF receptor/ErbB2 kinase activation revealed by luciferase fragment complementation imaging

21 January 2018

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Structure of the extracellular region of HER3 reveals an interdomain tether

21 January 2018

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Off-target effects of epidermal growth factor receptor antagonists mediate retinal ganglion cell disinhibited axon growth

21 January 2018

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ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner

21 January 2018

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ErbB receptors modulation in different types of peripheral nerve regeneration.

21 January 2018

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Schwann cell mitosis in response to regenerating peripheral axons in vivo

21 January 2018

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Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ANA.24688

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3 April 2018

release_hmoqzc7e3rfmpep5r63ledbeqq

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/hmoqzc7e3rfmpep5r63ledbeqq

mapped directly with Wikidata item

24 November 2022

based on heuristic

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3 April 2018