Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion. (Q51304272)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

title

Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

Bart Staels

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

François Pattou

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

Julien Thévenet

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

Benoit Deprez

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

Amar Abderrahmani

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

author name string

Julie Kerr-Conte

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

Valéry Gmyr

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

Gurvan Queniat

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

Ericka Moerman

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

Cédric Beaucamps

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

Nathalie Delalleau

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

Iuliana Popescu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

Willy J Malaisse

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

Abdullah Sener

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

language of work or name

English

0 references

publication date

20 April 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

6 March 2020

page(s)

512-517

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25894829 AND SRC:MED&resulttype=core&format=json

Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future

6 March 2020

cites work

1 reference

Sodium glucose co-transporter 2 inhibitors: blocking renal tubular reabsorption of glucose to improve glycaemic control in patients with diabetes

21 January 2018

1 reference

Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus

21 January 2018

1 reference

Sodium glucose cotransporter 2 inhibitors as a new treatment for diabetes mellitus.

21 January 2018

1 reference

Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production.

21 January 2018

1 reference

Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients

21 January 2018

1 reference

From mice to men: insights into the insulin resistance syndromes

21 January 2018

1 reference

Hepatic and peripheral insulin resistance: a common feature of type 2 (non-insulin-dependent) and type 1 (insulin-dependent) diabetes mellitus

21 January 2018

1 reference

Quantification of the relative impairment in actions of insulin on hepatic glucose production and peripheral glucose uptake in non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

Role of liver in pathophysiology of NIDDM

21 January 2018

1 reference

Role of hyperglucagonemia in maintenance of increased rates of hepatic glucose output in type II diabetics

21 January 2018

1 reference

Studies of pancreatic alpha cell function in normal and diabetic subjects

21 January 2018

1 reference

Glucagon control of fasting glucose in man.

21 January 2018

1 reference

Adaptive changes of human islets to an obesogenic environment in the mouse

21 January 2018

1 reference

RETRACTED: Betatrophin: a hormone that controls pancreatic β cell proliferation

21 January 2018

1 reference

The maturity-onset diabetes of the young (MODY1) transcription factor HNF4α regulates expression of genes required for glucose transport and metabolism

21 January 2018

1 reference

Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis

21 January 2018

1 reference

A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 alpha gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an ashkenazi jewish population.

21 January 2018

1 reference

Dapagliflozin, a selective SGLT2 inhibitor, improves glucose homeostasis in normal and diabetic rats

21 January 2018

1 reference

Glucagon regulates its own synthesis by autocrine signaling

21 January 2018

1 reference

Glucose regulation of glucagon secretion

21 January 2018

1 reference

Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes

21 January 2018

1 reference

The SLC2 (GLUT) family of membrane transporters

21 January 2018

1 reference

Remogliflozin etabonate, in a novel category of selective low-affinity sodium glucose cotransporter (SGLT2) inhibitors, exhibits antidiabetic efficacy in rodent models

21 January 2018

1 reference

SGLT2 deletion improves glucose homeostasis and preserves pancreatic beta-cell function

21 January 2018

1 reference

Effects of a new SGLT2 inhibitor, luseogliflozin, on diabetic nephropathy in T2DN rats

21 January 2018

1 reference

Improved glycemic control in mice lacking Sglt1 and Sglt2.

21 January 2018

1 reference

Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models

21 January 2018

1 reference

Empagliflozin, a novel potent and selective SGLT-2 inhibitor, improves glycaemic control alone and in combination with insulin in streptozotocin-induced diabetic rats, a model of type 1 diabetes mellitus

21 January 2018

1 reference

Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats

21 January 2018

1 reference

Selective SGLT2 inhibition by tofogliflozin reduces renal glucose reabsorption under hyperglycemic but not under hypo- or euglycemic conditions in rats.

21 January 2018

1 reference

Hypoglycemia in diabetes.

21 January 2018

1 reference

Fasting hyperglycemia in non-insulin-dependent diabetes mellitus: contributions of excessive hepatic glucose production and impaired tissue glucose uptake

21 January 2018

1 reference

Glucose transport by acinar cells in rat parotid glands.

21 January 2018

1 reference

A novel missense mutation in SLC5A2 encoding SGLT2 underlies autosomal-recessive renal glucosuria and aminoaciduria

21 January 2018

1 reference

Upgrading pretransplant human islet culture technology requires human serum combined with media renewal.

21 January 2018

1 reference

Transcriptomes of the major human pancreatic cell types.

21 January 2018

1 reference

CXCL10 impairs beta cell function and viability in diabetes through TLR4 signaling.

21 January 2018

1 reference

Efficient gene delivery and silencing of mouse and human pancreatic islets

21 January 2018

1 reference

In vitro characterization and pharmacokinetics of dapagliflozin (BMS-512148), a potent sodium-glucose cotransporter type II inhibitor, in animals and humans

21 January 2018

1 reference

Tolbutamide controls glucagon release from mouse islets differently than glucose: involvement of K(ATP) channels from both α-cells and δ-cells

21 January 2018

1 reference

Human high-density lipoprotein particles prevent activation of the JNK pathway induced by human oxidised low-density lipoprotein particles in pancreatic beta cells

21 January 2018

1 reference

Evidence based selection of housekeeping genes

21 January 2018

1 reference

In vitro-in vivo correlation of the inhibition potency of sodium-glucose cotransporter inhibitors in rat: a pharmacokinetic and pharmacodynamic modeling approach

21 January 2018

1 reference

12 December 2020

Identification and purification of functional human beta-cells by a new specific zinc-fluorescent probe

1 reference

12 December 2020

Failure of glucagon suppression contributes to postprandial hyperglycaemia in IDDM

1 reference

12 December 2020

Common Variants of the Hepatocyte Nuclear Factor-4 P2 Promoter Are Associated With Type 2 Diabetes in the U.K. Population

1 reference

12 December 2020

Dapagliflozin, an SGLT2 inhibitor for the treatment of type 2 diabetes

1 reference

12 December 2020

Tofogliflozin, a potent and highly specific sodium/glucose cotransporter 2 inhibitor, improves glycemic control in diabetic rats and mice

1 reference

12 December 2020

Antidiabetic effects of SGLT2-selective inhibitor ipragliflozin in streptozotocin-nicotinamide-induced mildly diabetic mice

1 reference

12 December 2020