A unique allosteric insulin receptor monoclonal antibody that prevents hypoglycemia in the SUR-1(/( mouse model of KATP hyperinsulinism. (Q51244136)

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21 March 2020

title

A unique allosteric insulin receptor monoclonal antibody that prevents hypoglycemia in the SUR-1-/- mouse model of KATP hyperinsulinism (English)

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21 March 2020

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4

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21 March 2020

Diva D De León

7

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21 March 2020

author name string

Lawrenshey Charles

2

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21 March 2020

John Corbin

3

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21 March 2020

Kirk Johnson

5

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Paul Rubin

6

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21 March 2020

Puja Patel

1

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21 March 2020

publication date

1 June 2018

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21 March 2020

published in

Monoclonal Antibodies

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21 March 2020

volume

10

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issue

5

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21 March 2020

page(s)

796-802

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Attenuation of Insulin Action by an Allosteric Insulin Receptor Antibody in Healthy Volunteers

21 March 2020

cites work

1 reference

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High Risk of Diabetes and Neurobehavioral Deficits in Individuals With Surgically Treated Hyperinsulinism.

2 November 2018

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Inhibition of insulin receptor function by a human, allosteric monoclonal antibody: a potential new approach for the treatment of hyperinsulinemic hypoglycemia.

2 November 2018

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Clinical presentation and management of children with diffuse and focal hyperinsulinism: a review of 223 cases.

2 November 2018

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Measuring energy metabolism in the mouse - theoretical, practical, and analytical considerations

2 November 2018

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Monogenic hyperinsulinemic hypoglycemia: current insights into the pathogenesis and management

2 November 2018

1 reference

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GLP-1 receptor antagonist exendin-(9-39) elevates fasting blood glucose levels in congenital hyperinsulinism owing to inactivating mutations in the ATP-sensitive K channel

2 November 2018

1 reference

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Glucose metabolism in 105 children and adolescents after pancreatectomy for congenital hyperinsulinism

2 November 2018

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Inhibition of ADRP prevents diet-induced insulin resistance

2 November 2018

1 reference

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Exendin-(9-39) corrects fasting hypoglycemia in SUR-1-/- mice by lowering cAMP in pancreatic beta-cells and inhibiting insulin secretion

2 November 2018

1 reference

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Long-term neurodevelopmental outcome in conservatively treated congenital hyperinsulinism

2 November 2018

1 reference

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Physiological and pathophysiological roles of ATP-sensitive K channels

2 November 2018

1 reference

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Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose

2 November 2018

1 reference

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Sur1 knockout mice. A model for K(ATP) channel-independent regulation of insulin secretion

2 November 2018

1 reference

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Molecular biology of adenosine triphosphate-sensitive potassium channels

2 November 2018

1 reference

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Puberty decreases insulin sensitivity

2 November 2018

1 reference

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10.1080/19420862.2018.1457599

2 November 2018

Identifiers

DOI

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21 March 2020

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21 March 2020

PubMed publication ID

29589989

1 reference